Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 9/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | TEK | Q02763 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 4/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | ABL2 | P42684 | 3/20 | 0.36 |
| ▸ | C1S | P09871 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.32 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.32 |
| ▸ | IGF1R | P08069 | 5/20 | 0.32 |
| ▸ | INSR | P06213 | 4/20 | 0.32 |
| ▸ | LYN | P07948 | 2/20 | 0.32 |
| ▸ | RET | P07949 | 2/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | LATS1 | O95835 | 1/20 | 0.32 |
| ▸ | YES1 | P07947 | 1/20 | 0.32 |
| ▸ | HCK | P08631 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30940936 | 0.86 | CA2 (0.39) | C1SCA2METTL3 | |
| SCHEMBL25049217 | 0.84 | C1S (0.36) | SRCLCKKDRTEKABL1 | |
| SCHEMBL25049204 | 0.80 | METTL3 (0.39) | SRCLCKKDRTEKABL1 | |
| SCHEMBL25048024 | 0.78 | SRC (0.35) | SRCLCKKDRTEKABL1 | |
| SCHEMBL25047567 | 0.78 | C1S (0.36) | SRCLCKKDRTEKABL1 | |
| SCHEMBL25048891 | 0.78 | IGF1R (0.36) | SRCLCKKDRTEKEGFR | |
| SCHEMBL25049346 | 0.78 | KCNH2 (0.36) | SRCLCKKDRTEKABL1 | |
| SCHEMBL25048047 | 0.77 | C1S (0.33) | SRCLCKABL1EGFRABL2 | |
| SCHEMBL25048943 | 0.77 | C1S (0.35) | SRCLCKKDRABL1EGFR | |
| SCHEMBL25048727 | 0.76 | SRC (0.35) | SRCLCKABL1EGFRABL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017152-A1 | SPECIFIC SMALL MOLECULE INHIBITORS THAT BLOCK KMT9 METHYLTRANSFERASE ACTIVITY AND FUNCTION | ALBERT-LUDWIGS-UNIVERSITÄT FREIBURG (DE) | 2023-02-16 | — | — | WO | disclosed |