Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.33 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
| ▸ | KMO | O15229 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.30 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16636772 | 0.77 | KMO (0.37) | EGLN1NOTUMHTR3EHTR3BHTR3A | |
| SCHEMBL16637079 | 0.74 | CSNK2A1 (0.37) | CSNK2A1 | |
| SCHEMBL11211641 | 0.74 | CASP6 (0.40) | EGLN1 | |
| SCHEMBL27474584 | 0.74 | LMNA (0.35) | — | |
| SCHEMBL14584685 | 0.74 | C1R (0.31) | — | |
| SCHEMBL25051724 | 0.72 | NOTUM (0.34) | EGLN1NOTUMHTR3EHTR3BHTR3A | |
| SCHEMBL24579692 | 0.70 | AHR (0.32) | CSNK2A1 | |
| SCHEMBL11217658 | 0.70 | GAA (0.39) | EGLN1 | |
| SCHEMBL27248741 | 0.70 | PGK1 (0.46) | KDR | |
| SCHEMBL25486563 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023018699-A1 | SELECTIVE KRAS INHIBITORS | ERASCA, INC. (US) | 2023-02-16 | — | — | WO | disclosed |