Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 2/20 | 0.51 |
| ▸ | TAS2R38 | P59533 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14868330 | 0.84 | TAS2R38 (0.41) | EPHX1TAS2R38ALDH1A1HSD17B10CYP3A4 | |
| Hydrochloric Acid SCHEMBL28219362 | 0.83 | TAS2R38 (0.39) | EPHX1TAS2R38ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL25049852 | 0.77 | ALDH1A1 (0.46) | ALDH1A1CYP3A4GAAKMT2AMEN1 | |
| SCHEMBL2001630 | 0.77 | TAS2R38 (0.46) | EPHX1TAS2R38ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL11689139 | 0.76 | EPHX1 (0.58) | EPHX1TAS2R38ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL11763947 | 0.75 | EPHX1 (0.67) | EPHX1TAS2R38ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL730314 | 0.74 | ALDH1A1 (0.80) | EPHX1TAS2R38ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL4097497 | 0.73 | EPHX1 (0.54) | EPHX1TAS2R38ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL11136394 | 0.73 | LMNA (0.53) | EPHX1TAS2R38ALDH1A1HSD17B10CYP3A4 | |
| SCHEMBL3421577 | 0.72 | ALDH1A1 (0.63) | EPHX1TAS2R38ALDH1A1HSD17B10CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023017400-A1 | METFORMIN CONJUGATES AND THERAPEUTIC USE THEREOF | UNIVERSITA' DI PISA (IT) | 2023-02-16 | — | — | WO | disclosed |