SCHEMBL25051170

SCHEMBL25051170

c1ccc(-c2nc(-c3ccccc3)nc(-c3cc(-n4c5cc6ccccc6cc5c5cc6ccccc6cc54)cc4oc5ccccc5c34)n2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.33
MAPT P10636 5/20 0.32
KDM4E B2RXH2 5/20 0.32
SMN1; SMN2 Q16637 3/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
TERT O14746 2/20 0.32
SIRT2 Q8IXJ6 1/20 0.31
SIRT1 Q96EB6 1/20 0.31
LMNA P02545 3/20 0.31
MAPK1 P28482 2/20 0.31
HSD17B10 Q99714 2/20 0.31
ADORA3 P0DMS8 1/20 0.31
ALOX15 P16050 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31
ADORA1 P30542 1/20 0.31
ALDH1A1 P00352 4/20 0.31
HPGD P15428 2/20 0.31
PTGER4 P35408 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23204080 0.97 KDM4E (0.33) TSHRMAPTKDM4ESMN1; SMN2NPC1
SCHEMBL23738343 0.95 PLA2G2A (0.33) TSHRMAPTKDM4ESMN1; SMN2TERT
SCHEMBL23738583 0.95 KDM4E (0.31) TSHRKDM4EATML3MBTL1
SCHEMBL23737419 0.95 KDM4E (0.31) TSHRKDM4EATML3MBTL1
SCHEMBL23738648 0.95 KDM4E (0.35) TSHRKDM4ESMN1; SMN2SIRT2SIRT1
SCHEMBL25050772 0.95 PTGER4 (0.34) TSHRMAPTKDM4EALDH1A1HPGD
SCHEMBL23592261 0.94 PLA2G2A (0.32) TSHR
SCHEMBL23592266 0.94 PLA2G2A (0.30) TSHRPTGER4
SCHEMBL23738426 0.94 KDM4E (0.31) TSHRKDM4EATML3MBTL1
SCHEMBL25049333 0.94 CHEK2 (0.34) TSHRMAPTKDM4ESMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230128360-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE LT MATERIALS CO., LTD. (KR) 2023-04-27 US disclosed
US-20230049674-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2023-02-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230128360-A1 HETEROCYCLIC COMPOUND, ORGANIC LIGHT EMITTING DEVICE COMPRISING SAME, COMPOSITION FOR ORGANIC LAYER OF ORGANIC LIGHT EMITTING DEVICE CRY1, ORC3, ODC1 TSHR 4641/4885MAPT 950/4885KDM4E 3080/4885
US-20230049674-A1 ORGANIC LIGHT EMITTING DEVICE CRY2, ELOVL1, CRY1 TSHR 2926/4885MAPT 1921/4885KDM4E 2327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.