Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 7/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CTSV | O60911 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CTSC | P53634 | 1/20 | 0.34 |
| ▸ | CTSF | Q9UBX1 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19614475 | 1.00 | TACR1 (0.35) | TACR1SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL1057324 | 0.85 | KMT2A (0.38) | MEN1KMT2ASIGMAR1 | |
| SCHEMBL19627471 | 0.83 | LMNA (0.36) | TACR1SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL19628503 | 0.83 | LMNA (0.36) | TACR1SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL19627465 | 0.83 | LMNA (0.36) | TACR1SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL15029188 | 0.82 | MEN1 (0.34) | TACR1SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL2085683 | 0.74 | — | — | |
| SCHEMBL19629072 | 0.72 | TACR1 (0.37) | TACR1SLC6A4MEN1KMT2ALMNA | |
| SCHEMBL1054202 | 0.71 | L3MBTL1 (0.40) | MEN1KMT2ALMNAOPRM1KCNH2 | |
| SCHEMBL31504154 | 0.67 | CTSV (0.37) | CTSVCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025083472-A2 | PROTAC COMPOUNDS BINDING KEAP1 UBIQUITIN LIGASE FOR TARGETED PROTEIN DEGRADATION | SEED THERAPEUTICS US, INC. (US) | 2025-04-24 | — | — | WO | disclosed |
| WO-2023018699-A1 | SELECTIVE KRAS INHIBITORS | ERASCA, INC. (US) | 2023-02-16 | — | — | WO | disclosed |