SCHEMBL31504154

SCHEMBL31504154

O=C1OC(COCc2ccccc2)(C(Cl)(Cl)Cl)N2CCCC12

nearest known ligand 0.37

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CTSV O60911 1/20 0.37
CTSL P07711 1/20 0.37
CTSB P07858 1/20 0.37
CTSS P25774 1/20 0.37
CTSK P43235 1/20 0.37
CTSC P53634 1/20 0.37
CTSF Q9UBX1 1/20 0.37
PREP P48147 2/20 0.34
FKBP1A P62942 2/20 0.34
CYP3A4 P08684 2/20 0.33
HCRTR1 O43613 1/20 0.33
HCRTR2 O43614 1/20 0.33
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19614475 0.67 TACR1 (0.35) CTSVCTSLCTSBCTSSCTSK
SCHEMBL25051753 0.67 TACR1 (0.35) CTSVCTSLCTSBCTSSCTSK
SCHEMBL19627471 0.62 LMNA (0.36) CTSVCTSLCTSBCTSSCTSK
SCHEMBL19628503 0.62 LMNA (0.36) CTSVCTSLCTSBCTSSCTSK
SCHEMBL19627465 0.62 LMNA (0.36) CTSVCTSLCTSBCTSSCTSK
SCHEMBL24736773 0.60 LMNA (0.36) CTSVCTSLCTSBCTSSCTSK
SCHEMBL25297066 0.60 PSEN1 (0.39) CTSVCTSLCTSBCTSSCTSK
SCHEMBL4654483 0.59 TSHR (0.48)
SCHEMBL14868111 0.59 ALDH1A1 (0.30) CYP3A4CYP2C9CYP2C19
SCHEMBL19101766 0.59 IDO1 (0.44) CTSVCTSLCTSBCTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025083472-A2 PROTAC COMPOUNDS BINDING KEAP1 UBIQUITIN LIGASE FOR TARGETED PROTEIN DEGRADATION SEED THERAPEUTICS US, INC. (US) 2025-04-24 WO disclosed