SCHEMBL25052845

SCHEMBL25052845

C=Cc1c(C)oc2ccc3c4ccccc4oc3c12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PGR P06401 1/20 0.38
MAPT P10636 5/20 0.36
KDM4E B2RXH2 4/20 0.36
ALOX5 P09917 1/20 0.35
MAOA P21397 3/20 0.35
CA2 P00918 1/20 0.35
AHR P35869 2/20 0.34
ALDH1A1 P00352 3/20 0.34
LMNA P02545 2/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HPGD P15428 2/20 0.34
MAPK1 P28482 1/20 0.34
TP53 P04637 1/20 0.34
ATM Q13315 1/20 0.34
TSHR P16473 1/20 0.34
HTT P42858 1/20 0.34
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21615029 0.80 KDM4E (0.47) MAPTKDM4EMAOACA2AHR
SCHEMBL22182042 0.75 ALOX5 (0.35) PGRMAPTKDM4EALOX5MAOA
SCHEMBL22908129 0.74 L3MBTL1 (0.39) PGRMAPTKDM4EALOX5MAOA
SCHEMBL23242811 0.74 MAPT (0.50) PGRMAPTKDM4EALOX5MAOA
SCHEMBL1635599 0.73 MAPT (0.48) MAPTKDM4EALOX5MAOAAHR
SCHEMBL12811329 0.72 ALOX5 (0.32) MAPTKDM4EALOX5ALDH1A1MEN1
SCHEMBL18348602 0.71 PGR (0.41) PGRKDM4EALOX5MAOAAHR
SCHEMBL24662828 0.71 HPGD (0.42) PGRMAPTKDM4EALOX5MAOA
SCHEMBL24039790 0.70 AHR (0.46) PGRMAPTKDM4EALOX5MAOA
SCHEMBL14476381 0.70 AHR (0.46) PGRMAPTKDM4EALOX5MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230050369-A1 ORGANIC ELECTROLUMINESCENT ELEMENT, COMPOUND AND ELECTRONIC DEVICE IDEMITSU KOSAN CO.,LTD. (JP) 2023-02-16 US disclosed