SCHEMBL22908129

SCHEMBL22908129

C=C/C=C\c1oc2ccc3c4ccccc4oc3c2c1C

nearest known ligand 0.39

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.39
PGR P06401 1/20 0.35
MAOA P21397 3/20 0.35
KDM4E B2RXH2 4/20 0.32
MAPT P10636 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CYP3A4 P08684 1/20 0.32
PKM P14618 1/20 0.32
RECQL P46063 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MAPK1 P28482 1/20 0.32
ATM Q13315 1/20 0.32
ALDH1A1 P00352 1/20 0.31
AHR P35869 1/20 0.31
JAK2 O60674 1/20 0.31
ZAP70 P43403 1/20 0.31
SYK P43405 1/20 0.31
ALOX5 P09917 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22908095 0.85 L3MBTL1 (0.42) L3MBTL1MAOAKDM4EMAPTMEN1
SCHEMBL20019274 0.82 L3MBTL1 (0.54) L3MBTL1MAOAKDM4EMAPTKMT2A
SCHEMBL25615240 0.79 HNF4A (0.47) L3MBTL1KDM4EMAPTMEN1KMT2A
SCHEMBL19993450 0.77 L3MBTL1 (0.33) L3MBTL1MAPTALOX5
SCHEMBL22908094 0.77 MAOA (0.47) L3MBTL1PGRMAOAKDM4EMAPT
SCHEMBL22617891 0.75 L3MBTL1 (0.40) L3MBTL1MAOAKDM4EMAPTMEN1
SCHEMBL25768579 0.75 L3MBTL1 (0.33) L3MBTL1
SCHEMBL25052845 0.74 PGR (0.38) PGRMAOAKDM4EMAPTMEN1
SCHEMBL22926681 0.74 MEN1 (0.32) PGRKDM4EMAPTMEN1KMT2A
SCHEMBL24906623 0.73 L3MBTL1 (0.34) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210020842-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2021-01-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210020842-A1 ORGANIC LIGHT-EMITTING DEVICE OR10J3, OR51E2, LOXL1 L3MBTL1 747/4885PGR 1482/4885MAOA 147/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.