Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.33 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.33 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14898382 | 0.93 | ALDH1A1 (0.40) | TSHRALDH1A1LMNAABCC4MAPT | |
| SCHEMBL18155571 | 0.83 | LMNA (0.38) | ALDH1A1LMNAABCC4MAPT | |
| SCHEMBL26060542 | 0.83 | LMNA (0.38) | ALDH1A1LMNAABCC4MAPT | |
| SCHEMBL18426534 | 0.74 | ALOX15 (0.34) | TSHRALDH1A1LMNAALOX15 | |
| SCHEMBL19289866 | 0.73 | ALDH1A1 (0.39) | TSHRALDH1A1LMNAABCC4MAPT | |
| SCHEMBL13282208 | 0.73 | ALDH1A1 (0.39) | TSHRALDH1A1LMNAABCC4MAPT | |
| SCHEMBL13282112 | 0.73 | ALDH1A1 (0.39) | TSHRALDH1A1LMNAABCC4MAPT | |
| Acetone SCHEMBL4681458 | 0.72 | TSHR (0.74) | TSHRALDH1A1LMNAPLA2G2CFAAH | |
| SCHEMBL18488492 | 0.72 | ALDH1A1 (0.34) | ALDH1A1LMNAABCC4MAPT | |
| Acetic Acid SCHEMBL28115505 | 0.71 | TSHR (0.70) | TSHRALDH1A1LMNAPLA2G2CFAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3052121-B1 | WNT COMPOSITIONS AND METHODS FOR PURIFICATION | UNIV LELAND STANFORD JUNIOR (US) | 2023-02-22 | — | — | EP | disclosed |