Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26060542 | 1.00 | LMNA (0.38) | LMNAALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL18773741 | 0.92 | SOAT1 (0.36) | SOAT1 | |
| SCHEMBL14898382 | 0.90 | ALDH1A1 (0.40) | LMNAALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL25058910 | 0.83 | TSHR (0.43) | LMNAALDH1A1MAPTABCC4 | |
| Acetic Acid SCHEMBL3194491 | 0.75 | MAPT (0.48) | LMNAALDH1A1MAPTUSP2CYP3A4 | |
| Acetic Acid SCHEMBL3194485 | 0.75 | MAPT (0.48) | LMNAALDH1A1MAPTUSP2CYP3A4 | |
| Acetic Acid SCHEMBL28522340 | 0.73 | MAPT (0.57) | LMNAALDH1A1MAPTUSP2CYP3A4 | |
| Acetic Acid SCHEMBL28514189 | 0.73 | MAPT (0.57) | LMNAALDH1A1MAPTUSP2CYP3A4 | |
| SCHEMBL24473563 | 0.73 | ACLY (0.35) | USP2CYP3A4RECQLSOAT1 | |
| SCHEMBL18155569 | 0.73 | ACLY (0.35) | USP2CYP3A4RECQLSOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2508531-B1 | Stitched polypeptides | HARVARD COLLEGE (US) | 2016-10-19 | — | — | EP | disclosed |