Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 3/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.38 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30954769 | 0.79 | ALDH1A1 (0.45) | MEN1KMT2ATSHRALDH1A1KIF11 | |
| SCHEMBL29141867 | 0.79 | TAS2R14 (0.41) | MEN1KMT2ATSHRALDH1A1KIF11 | |
| SCHEMBL29141880 | 0.79 | ALDH1A1 (0.39) | HSP90AA1MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL5596033 | 0.79 | ALDH1A1 (0.50) | HSP90AA1MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL25060875 | 0.79 | NPC1 (0.41) | TSHRALDH1A1ESR1ESR2KIF11 | |
| SCHEMBL28294522 | 0.78 | KIF11 (0.46) | TSHRALDH1A1KIF11RAB9A | |
| SCHEMBL29141857 | 0.78 | ALDH1A1 (0.38) | HSP90AA1MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL29141878 | 0.77 | ALDH1A1 (0.36) | MEN1KMT2ATSHRALDH1A1KIF11 | |
| SCHEMBL30954775 | 0.76 | ALDH1A1 (0.49) | MEN1KMT2ATSHRALDH1A1KIF11 | |
| SCHEMBL25176323 | 0.76 | ESR2 (0.56) | HSP90AA1MEN1KMT2ATSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11780864-B2 | Rhenium(V) alkylidyne complexes and methods of use and preparation thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-10-10 | — | — | US | disclosed |
| US-11780864-B2 | Rhenium(V) alkylidyne complexes and methods of use and preparation thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-10-10 | — | — | US | disclosed |
| US-20230059662-A1 | Rhenium(V) Alkylidyne Complexes and Methods of Use and Preparation Thereof | THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY (CN) | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230059662-A1 | Rhenium(V) Alkylidyne Complexes and Methods of Use and Preparation Thereof | RNF168, CCND2, RAD50 | HSP90AA1 4349/4885MEN1 349/4885KMT2A 1958/4885 |
| US-11780864-B2 | Rhenium(V) alkylidyne complexes and methods of use and preparation thereof | RNF168, CCND2, RAD50 | HSP90AA1 4349/4885MEN1 349/4885KMT2A 1958/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.