SCHEMBL25065

SCHEMBL25065

CCCCCCc1[c]cccc1Cl

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 6/20 0.42
KDM4E B2RXH2 2/20 0.40
LMNA P02545 2/20 0.40
LIPG Q9Y5X9 1/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
ESR1 P03372 2/20 0.35
ADRA2A P08913 2/20 0.35
ADORA3 P0DMS8 2/20 0.35
TACR2 P21452 2/20 0.35
SLC6A2 P23975 2/20 0.35
SLC6A4 P31645 2/20 0.35
SLC6A3 Q01959 2/20 0.35
TP53 P04637 2/20 0.35
CYP3A4 P08684 2/20 0.35
ALDH1A1 P00352 1/20 0.35
SHBG P04278 1/20 0.35
HSPD1 P10809 1/20 0.35
ADRB3 P13945 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6558277 1.00 KCNH2 (0.42) KCNH2KDM4ELMNALIPGMEN1
SCHEMBL10661017 1.00 KCNH2 (0.42) KCNH2KDM4ELMNALIPGMEN1
SCHEMBL19405573 0.98 KCNH2 (0.39) KCNH2KDM4ELMNALIPGMEN1
SCHEMBL24998 0.93 KDM4E (0.35) KCNH2KDM4ELMNAMEN1KMT2A
SCHEMBL9322491 0.85 LMNA (0.31) KDM4ELMNATSHR
SCHEMBL21523367 0.80 LIPG (0.49) KCNH2LIPGMEN1KMT2ATP53
SCHEMBL21523356 0.80 LIPG (0.49) KCNH2LIPGMEN1KMT2ATP53
SCHEMBL21523328 0.80 LIPG (0.49) KCNH2LIPGMEN1KMT2ATP53
SCHEMBL21523330 0.80 LIPG (0.49) KCNH2LIPGMEN1KMT2ATP53
SCHEMBL21523355 0.80 LIPG (0.49) KCNH2LIPGMEN1KMT2ATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107004906-B Magnesium-containing electrolyte 富士胶片和光纯药株式会社 2020-04-21 CN disclosed
US-10367231-B2 Magnesium-containing electrolytic solution FUJIFILM WAKO PURE CHEMICAL CORPORATION (JP) 2019-07-30 US disclosed
EP-3226340-B1 MAGNESIUM-CONTAINING ELECTROLYTIC SOLUTION FUJIFILM WAKO PURE CHEMICAL CORP (JP) 2018-11-07 EP disclosed
US-20170331154-A1 MAGNESIUM-CONTAINING ELECTROLYTIC SOLUTION WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 2017-11-16 US disclosed
EP-3226340-A1 MAGNESIUM-CONTAINING ELECTROLYTIC SOLUTION Wako Pure Chemical Industries, Ltd. (JP) 2017-10-04 EP disclosed
EP-2588480-A2 3,4-DIHYDROPYRROLO[1,2-A]PYRAZINE-2,8(1H)-DICARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF& xA; SANOFI (FR) 2013-05-08 EP disclosed
WO-2011161537-A2 3,4-DIHYDROPYRROLO[1,2-A]PYRAZINE-2,8(1H)-DICARBOXAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF SANOFI (FR) 2011-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10367231-B2 Magnesium-containing electrolytic solution CA1, CA3, CA2 KCNH2 67/4885KDM4E 3595/4885LMNA 2142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.