Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | ADH1B | P00325 | 1/20 | 0.35 |
| ▸ | ADH1C | P00326 | 1/20 | 0.35 |
| ▸ | ADH1A | P07327 | 1/20 | 0.35 |
| ▸ | ADH4 | P08319 | 1/20 | 0.35 |
| ▸ | ADH7 | P40394 | 1/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.35 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28001808 | 0.86 | SPHK1 (0.42) | DNM1OPRM1SPHK1TSHR | |
| SCHEMBL29044204 | 0.84 | OPRM1 (0.46) | DNM1OPRM1SPHK1LMNAADH1B | |
| SCHEMBL27537259 | 0.84 | DNM1 (0.47) | DNM1SPHK1GBA1LPAR1LPAR3 | |
| SCHEMBL27369699 | 0.84 | DNM1 (0.47) | DNM1SPHK1GBA1LPAR1LPAR3 | |
| SCHEMBL27386764 | 0.84 | DNM1 (0.47) | DNM1SPHK1GBA1LPAR1LPAR3 | |
| SCHEMBL27410575 | 0.84 | DNM1 (0.47) | DNM1SPHK1GBA1LPAR1LPAR3 | |
| SCHEMBL10525652 | 0.84 | DNM1 (0.47) | DNM1SPHK1GBA1LPAR1LPAR3 | |
| SCHEMBL19744245 | 0.84 | OPRM1 (0.46) | DNM1OPRM1SPHK1LMNAADH1B | |
| SCHEMBL28432813 | 0.84 | OPRM1 (0.46) | DNM1OPRM1SPHK1LMNAADH1B | |
| SCHEMBL8638148 | 0.83 | DNM1 (0.42) | DNM1OPRM1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230055805-A1 | TOLL-LIKE RECEPTOR LIGANDS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2023-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230055805-A1 | TOLL-LIKE RECEPTOR LIGANDS | TLR1, TLR4, TLR6 | DNM1 4206/4885OPRM1 571/4885SPHK1 312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.