Eprozinol

Eprozinol

SCHEMBL250679

COC(CN1CCN(CCC(O)c2ccccc2)CC1)c1ccccc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 8/20 0.60
GAA P10253 1/20 0.56
SLC6A4 P31645 2/20 0.53
SLC6A3 Q01959 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Eprozinol SCHEMBL317704 0.99 HTR1A (0.58) HTR1AGAASLC6A4SLC6A3
Eprozinol SCHEMBL6235398 0.99 HTR1A (0.58) HTR1AGAASLC6A4SLC6A3
Eprozinol SCHEMBL1649758 0.97 HTR1A (0.57) HTR1AGAASLC6A4SLC6A3
SCHEMBL17771711 0.82 GAA (0.61) GAASLC6A3
SCHEMBL7428354 0.81 GAA (0.73) HTR1AGAASLC6A4SLC6A3
Zipeprol SCHEMBL364352 0.79 GAA (0.47) GAA
SCHEMBL17771721 0.79 ALDH1A1 (0.49) GAA
Zipeprol SCHEMBL5563283 0.78 GAA (0.46) GAA
Zipeprol SCHEMBL363879 0.78 GAA (0.46) GAA
SCHEMBL17771722 0.77 HIF1A (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 355 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11124835-B2 Methods of diagnosing chronic obstructive pulmonary disease (COPD) using novel molecular biomarkers Transgenion—International Institute for Regenerative Translational Medicine GmbH (AT) 2021-09-21 US claimed
EP-3152330-B1 METHODS OF DIAGNOSING CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) USING NOVEL MOLECULAR BIOMARKERS TRANSGENION INT INSTITUTE FOR REGENERATIVE TRANSLATIONAL MEDICINE GMBH (AT) 2021-01-27 EP claimed
US-10604806-B2 Methods of diagnosing chronic obstructive pulmonary disease (COPD) using novel molecular biomarkers Transgenion—International Institute for Regenerative Translational Medicine GmbH (AT) 2020-03-31 US claimed
US-20170349947-A1 METHODS OF DIAGNOSING CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) USING NOVEL MOLECULAR BIOMARKERS TRANSGENION - INTERNATIONAL INSTITUTE FOR REGENERATIVE TRANSLATIONAL MEDICINE GMBH (AT) 2017-12-07 US claimed
US-20170335393-A1 METHODS OF DIAGNOSING CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) USING NOVEL MOLECULAR BIOMARKERS TRANSGENION - INTERNATIONAL INSTITUTE FOR REGENERATIVE TRANSLATIONAL MEDICINE GMBH (AT) 2017-11-23 US claimed
US-20170107574-A1 METHODS OF DIAGNOSING CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) USING NOVEL MOLECULAR BIOMARKERS TRANSGENION - INTERNATIONAL INSTITUTE FOR REGENERATIVE TRANSLATIONAL MEDICINE GMBH (AT) 2017-04-20 US claimed
EP-3152328-A2 METHODS OF DIAGNOSING CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) USING NOVEL MOLECULAR BIOMARKERS TRANSGENION-INTERNATIONAL INSTITUTE FOR REGENERATIVE TRANSLATIONAL MEDICINE GMBH (AT) 2017-04-12 EP claimed
EP-3152330-A1 METHODS OF DIAGNOSING CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) USING NOVEL MOLECULAR BIOMARKERS TRANSGENION-INTERNATIONAL INSTITUTE FOR REGENERATIVE TRANSLATIONAL MEDICINE GMBH (AT) 2017-04-12 EP claimed
EP-3152329-A2 METHODS OF DIAGNOSING CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) USING NOVEL MOLECULAR BIOMARKERS TRANSREGION-INTERNATIONAL INSTITUTE FOR TRANSLATIONAL MEDICINE GMBH (AT) 2017-04-12 EP claimed
WO-2015185658-A2 METHODS OF DIAGNOSING CHRONIC OBSTRUCTIVE PULMONARY DISEASE (COPD) USING NOVEL MOLECULAR BIOMARKERS MEDIZINISCHE UNIVERSITÄT WIEN (AT) 2015-12-10 WO claimed
US-20010006962-A1 FATTY ACID DERIVATIVES NORSK HYDRO ASA (NO) 2001-07-05 US claimed
CN-1294519-A Pharmaceutical composition containing a compound having an activity of promoting the absorption of an active ingredient INPHARMA SA (CH) 2001-05-09 CN claimed
WO-2001012584-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2001-02-22 WO claimed
EP-1073470-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2001-02-07 EP claimed
WO-2000061549-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061541-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000061537-A2 PHARMACEUTICAL COMPOUNDS NICOX S.A. (FR) 2000-10-19 WO claimed
WO-2000048636-A1 PHARMACEUTICAL COMPOSITIONS CONTAINING COMPOUNDS WITH ACTIVITY FOR THE ENHANCEMENT OF ABSORPTION OF ACTIVE INGREDIENTS INPHARMA S.A. (CH) 2000-08-24 WO claimed
EP-0977725-A1 NEW FATTY ACID DERIVATIVES NORSK HYDRO ASA (NO) 2000-02-09 EP claimed
WO-1998032718-A1 NEW FATTY ACID DERIVATIVES NORSK HYDRO ASA (NO) 1998-07-30 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010006962-A1 FATTY ACID DERIVATIVES HADH, NR1H2, NR1H3 HTR1A 1196/4885GAA 3658/4885SLC6A4 1798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.