Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 2/20 | 0.41 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30279156 | 1.00 | PSMB1 (0.41) | PSMB1PSMB5MEN1KMT2AKDM4E | |
| SCHEMBL30279167 | 0.85 | KDM4E (0.45) | PSMB1PSMB5MEN1KMT2AKDM4E | |
| SCHEMBL30279166 | 0.85 | KDM4E (0.45) | PSMB1PSMB5MEN1KMT2AKDM4E | |
| SCHEMBL25073774 | 0.85 | KDM4E (0.45) | PSMB1PSMB5MEN1KMT2AKDM4E | |
| SCHEMBL30279202 | 0.80 | KMT2A (0.42) | PSMB1PSMB5MEN1KMT2AKDM4E | |
| SCHEMBL25073869 | 0.80 | KMT2A (0.42) | PSMB1PSMB5MEN1KMT2AKDM4E | |
| SCHEMBL25073775 | 0.75 | KDM4E (0.45) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL30279125 | 0.75 | KDM4E (0.45) | MEN1KMT2AKDM4ENPC1ALDH1A1 | |
| SCHEMBL25073871 | 0.74 | KDM4E (0.43) | KDM4ENPC1ALDH1A1RXFP1POLB | |
| SCHEMBL30279192 | 0.74 | KDM4E (0.43) | KDM4ENPC1ALDH1A1RXFP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023021278-A1 | PHENYL- AND PYRIDOPYRAZOLE DERIVATIVES AS INHIBITORS OF DDR1 | REDX PHARMA PLC (GB) | 2023-02-23 | — | — | WO | disclosed |