Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.39 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.39 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 3/20 | 0.39 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 4/20 | 0.37 |
| ▸ | HRH2 | P25021 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24671522 | 0.92 | HSD11B1 (0.43) | HSD11B1GNAI3GNAO1GNAI1DRD3 | |
| SCHEMBL24475306 | 0.86 | HRH3 (0.42) | HSD11B1GNAI3GNAO1GNAI1DRD3 | |
| SCHEMBL26295530 | 0.85 | FAAH (0.43) | DRD3DRD2KCNH2HRH3CYP2D6 | |
| SCHEMBL26295658 | 0.83 | HRH3 (0.47) | HSD11B1GNAI3GNAO1GNAI1DRD3 | |
| SCHEMBL22520620 | 0.82 | MAOB (0.42) | GNAO1DRD3DRD2KCNH2HRH3 | |
| SCHEMBL24475305 | 0.81 | GNAO1 (0.39) | HSD11B1GNAO1DRD3DRD2HRH3 | |
| SCHEMBL25819363 | 0.81 | HRH3 (0.44) | DRD3DRD2KCNH2HRH3CYP2D6 | |
| SCHEMBL26295701 | 0.80 | HRH3 (0.48) | HSD11B1DRD3DRD2KCNH2HRH3 | |
| SCHEMBL26295527 | 0.80 | FAAH (0.46) | DRD3DRD2KCNH2HRH3CYP2D6 | |
| SCHEMBL22520684 | 0.79 | HRH3 (0.43) | GNAI3GNAO1GNAI1DRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023537-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BRUTON'S TYROSINE KINASE | ENDOTARGET INC. (US) | 2023-02-23 | — | — | WO | disclosed |