Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | DRD3 | P35462 | 2/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.42 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 4/20 | 0.38 |
| ▸ | HRH2 | P25021 | 3/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26295527 | 0.89 | FAAH (0.46) | FAAHDRD2DRD3HRH1HRH2 | |
| SCHEMBL26295522 | 0.86 | FAAH (0.46) | FAAHDRD2DRD3GNAI3GNAO1 | |
| SCHEMBL26295530 | 0.86 | FAAH (0.43) | FAAHDRD2DRD3HRH1HRH2 | |
| SCHEMBL25075230 | 0.84 | GNAI3 (0.51) | FAAHGNAI3GNAO1GNAI1ALDH1A1 | |
| SCHEMBL26263451 | 0.83 | CACNA2D1 (0.48) | FAAHALDH1A1SMN1; SMN2 | |
| SCHEMBL26224205 | 0.80 | FAAH (0.52) | FAAHDRD2GNAI3GNAO1GNAI1 | |
| SCHEMBL22520728 | 0.79 | HRH3 (0.43) | FAAHDRD2DRD3SIGMAR1HRH3 | |
| SCHEMBL27108178 | 0.79 | HSD11B1 (0.50) | FAAHSIGMAR1CHRM3ALDH1A1SMN1; SMN2 | |
| SCHEMBL24320685 | 0.79 | NCF1 (0.46) | DRD2DRD3GNAI3GNAO1GNAI1 | |
| SCHEMBL23560471 | 0.78 | FAAH (0.51) | FAAHGNAI3GNAO1GNAI1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023537-A1 | COMPOUNDS AND METHODS FOR THE TARGETED DEGRADATION OF BRUTON'S TYROSINE KINASE | ENDOTARGET INC. (US) | 2023-02-23 | — | — | WO | disclosed |