Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | CCR3 | P51677 | 4/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9820857 | 0.96 | CCR3 (0.41) | PLGCCR3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL18995298 | 0.84 | CCR3 (0.42) | PLGCCR3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL27818694 | 0.78 | NPC1 (0.43) | PLGCCR3SLC6A4SLC6A2SLC6A3 | |
| SCHEMBL29139845 | 0.77 | SIGMAR1 (0.47) | — | |
| SCHEMBL3358034 | 0.74 | GBA1 (0.59) | SLC6A4 | |
| SCHEMBL25075404 | 0.73 | SLC6A4 (0.45) | PLGSLC6A4SLC6A2SLC6A3 | |
| SCHEMBL9820952 | 0.73 | CYP19A1 (0.40) | — | |
| SCHEMBL11537058 | 0.72 | GBA1 (0.58) | SLC6A4 | |
| SCHEMBL8698749 | 0.72 | HMOX1 (0.41) | — | |
| SCHEMBL8701883 | 0.72 | CYP19A1 (0.40) | PLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |