Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | FUCA1 | P04066 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31056427 | 1.00 | CTSL (0.38) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL29320338 | 0.87 | CA12 (0.48) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL29325561 | 0.86 | CTSL (0.40) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL29321284 | 0.86 | ALDH1A1 (0.48) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL31056902 | 0.86 | CTSL (0.40) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL29320158 | 0.85 | CTSL (0.39) | CTSLCTSBCTSSCTSKMEN1 | |
| SCHEMBL25076845 | 0.82 | KDM4E (0.47) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL30988614 | 0.82 | KDM4E (0.47) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL31386223 | 0.77 | TAAR1 (0.50) | — | |
| SCHEMBL9786097 | 0.77 | HTR2A (0.37) | CTSLCTSBCTSSCTSKSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |
| WO-2024148274-A1 | COMPLEMENT INHIBITION | APELLIS PHARMACEUTICALS, INC. (US) | 2024-07-11 | — | — | WO | disclosed |