Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | HAVCR2 | Q8TDQ0 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 2/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19533512 | 0.80 | PCSK9 (0.50) | KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL10429722 | 0.74 | L3MBTL1 (0.48) | MAPK14KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL2262620 | 0.73 | TP53 (0.44) | KMT2AMEN1ALDH1A1POLBBACE1 | |
| SCHEMBL2262617 | 0.73 | TP53 (0.53) | KMT2AMEN1ALDH1A1MAPK1BACE1 | |
| SCHEMBL11012132 | 0.72 | AR (0.47) | KMT2AMEN1ALDH1A1ABL1POLB | |
| SCHEMBL10724036 | 0.71 | GLO1 (0.50) | TLR8 | |
| SCHEMBL23165700 | 0.71 | ABL1 (0.36) | ABL1 | |
| SCHEMBL29710146 | 0.71 | ABL1 (0.39) | NPC1RAB9AALDH1A1ABL1 | |
| SCHEMBL11796015 | 0.71 | ALDH1A1 (0.67) | TLR8TDP2KMT2AMEN1NPC1 | |
| SCHEMBL23165769 | 0.71 | ABL1 (0.39) | NPC1RAB9AALDH1A1ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023022497-A1 | SOS1 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-02-23 | — | — | WO | disclosed |