Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 3/20 | 0.65 |
| ▸ | HTR7 | P34969 | 4/20 | 0.48 |
| ▸ | HTR1A | P08908 | 3/20 | 0.48 |
| ▸ | HTR2A | P28223 | 2/20 | 0.48 |
| ▸ | HTR2C | P28335 | 2/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | HTR3A | P46098 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.46 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5540575 | 0.90 | ADRB1 (0.80) | ADRB1HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL234093 | 0.87 | ADRB1 (0.87) | ADRB1HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL30087959 | 0.80 | CHRNB2 (0.47) | ADRB1HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL12991 | 0.80 | ADRB1 (0.69) | ADRB1HTR7KCNH2NOTUMALOX5 | |
| SCHEMBL8264176 | 0.80 | ADRB1 (0.69) | ADRB1HTR7KCNH2NOTUMALOX5 | |
| SCHEMBL9881493 | 0.79 | ADRB1 (0.60) | ADRB1HTR7HTR1AHTR2AHTR2B | |
| SCHEMBL81365 | 0.79 | ADRB1 (1.00) | ADRB1HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL29391951 | 0.79 | ADRB1 (1.00) | ADRB1HTR7HTR1AHTR2AHTR2C | |
| SCHEMBL17281442 | 0.78 | ADRB1 (0.67) | ADRB1HTR7KCNH2NOTUMALOX5 | |
| SCHEMBL2051022 | 0.78 | HTR3A (0.57) | ADRB1HTR7HTR1AHTR2BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023022497-A1 | SOS1 INHIBITOR AND USE THEREOF | 주식회사 카나프테라퓨틱스 | 2023-02-23 | — | — | WO | disclosed |