Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 5/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.65 |
| ▸ | HTT | P42858 | 3/20 | 0.65 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.65 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.65 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.65 |
| ▸ | ALOX12 | P18054 | 5/20 | 0.55 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | TP53 | P04637 | 4/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | PPP1CA | P62136 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30253871 | 1.00 | P4HB (0.70) | P4HBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL25079096 | 0.90 | ALOX12 (0.69) | P4HBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL30253817 | 0.90 | ALOX12 (0.69) | P4HBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL30253958 | 0.85 | P4HB (0.53) | P4HBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL25079457 | 0.85 | P4HB (0.53) | P4HBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL1700908 | 0.83 | P4HB (0.98) | P4HBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL25079006 | 0.82 | P4HB (0.49) | P4HBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL30253616 | 0.82 | P4HB (0.49) | P4HBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL30253582 | 0.82 | TP53 (0.49) | P4HBALDH1A1MAPTKDM4EKMT2A | |
| SCHEMBL25079000 | 0.81 | ALOX12 (0.51) | P4HBALDH1A1MAPTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023020534-A1 | COMPOUNDS AND THEIR USES AS MIF INHIBITORS | NANJING IMMUNOPHAGE BIOTECH CO., LTD (CN) | 2023-02-23 | — | — | WO | disclosed |