Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 4/20 | 0.47 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.43 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.43 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | RORA | P35398 | 1/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.43 |
| ▸ | RORB | Q92753 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | FUT7 | Q11130 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | FDFT1 | P37268 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17132575 | 0.89 | RORC (0.49) | RORCCA2NR1I2RORANR1H2 | |
| SCHEMBL10609457 | 0.84 | CA2 (0.43) | CA2SMN1; SMN2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL23555151 | 0.79 | FUT7 (0.47) | CA2SMN1; SMN2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL7337427 | 0.79 | CA2 (0.48) | CA2SMN1; SMN2KCNJ1KCNH2ENPP2 | |
| SCHEMBL7216900 | 0.79 | CA2 (0.69) | CA2SMN1; SMN2 | |
| SCHEMBL19650023 | 0.78 | GRIN2D (0.41) | CA2SMN1; SMN2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL1769854 | 0.78 | GRIN2D (0.41) | CA2SMN1; SMN2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL9420098 | 0.77 | FUT7 (0.52) | CA2SMN1; SMN2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL10609576 | 0.77 | FUT7 (0.49) | CA2SMN1; SMN2GRIN2DGRIN2AGRIN2B | |
| SCHEMBL9927244 | 0.77 | FUT7 (0.49) | CA2SMN1; SMN2GRIN2DGRIN2AGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023156-A1 | ACID CERAMIDASE INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-02-23 | — | — | WO | disclosed |