Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.34 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.34 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25080995 | 0.86 | L3MBTL1 (0.36) | L3MBTL1RECQLHPGDMEN1KMT2A | |
| SCHEMBL25080723 | 0.81 | KDM1A (0.37) | KDM1AMAOAMAOBSMPD1HPGD | |
| SCHEMBL24809667 | 0.80 | MTNR1A (0.50) | L3MBTL1RECQLHPGDMEN1KMT2A | |
| SCHEMBL25080746 | 0.79 | CA12 (0.47) | MEN1KMT2ASMN1; SMN2ADORA3ADORA2A | |
| SCHEMBL25080994 | 0.78 | CA12 (0.41) | MEN1KMT2AADORA3ADORA2AADORA1 | |
| SCHEMBL25080979 | 0.78 | GHSR (0.42) | L3MBTL1RECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25080941 | 0.77 | ADAMTS4 (0.46) | L3MBTL1KMT2ASMN1; SMN2FAAHNPC1 | |
| SCHEMBL25080738 | 0.77 | L3MBTL1 (0.39) | L3MBTL1RECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL25080774 | 0.77 | L3MBTL1 (0.39) | L3MBTL1RECQLMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24810552 | 0.74 | CYP2E1 (0.46) | RECQLHPGDSMN1; SMN2MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023023156-A1 | ACID CERAMIDASE INHIBITORS AND USES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-02-23 | — | — | WO | disclosed |