SCHEMBL329641

SCHEMBL329641

CO[Si](CN1CCCCCC1)(OC)OC

nearest known ligand 0.42

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.35
GAA P10253 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
ALDH1A1 P00352 2/20 0.32
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 1/20 0.32
CARM1 Q86X55 1/20 0.31
PRMT6 Q96LA8 1/20 0.31
PRMT8 Q9NR22 1/20 0.31
CHRM5 P08912 1/20 0.31
ADRA2C P18825 1/20 0.31
LMNA P02545 1/20 0.31
HTT P42858 1/20 0.30
RECQL P46063 1/20 0.30
ATM Q13315 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1230677 1.00 HRH3 (0.35) HRH3GAAMEN1KMT2AALDH1A1
SCHEMBL2502895 0.97 CARM1 (0.32) HRH3CARM1PRMT6PRMT8LMNA
SCHEMBL1229552 0.78 CSNK2A2 (0.35) GAAMEN1KMT2AALDH1A1LMNA
SCHEMBL2508441 0.78 HRH3 (0.33) HRH3GAAMEN1KMT2AALDH1A1
SCHEMBL776376 0.78 SMN1; SMN2 (0.40) HRH3ALDH1A1TDP1TSHRHTT
SCHEMBL1995114 0.78 HRH3 (0.33) HRH3GAAMEN1KMT2AALDH1A1
SCHEMBL1459032 0.76 HRH3 (0.42) HRH3MEN1KMT2AALDH1A1CARM1
SCHEMBL2399087 0.76 HRH3 (0.32) HRH3MEN1KMT2AALDH1A1TSHR
SCHEMBL329482 0.76 HRH3 (0.32) HRH3MEN1KMT2AALDH1A1TSHR
SCHEMBL538032 0.76 CYP1A2 (0.35) MEN1KMT2ACHRM5LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 311 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118006010-A Modified conjugated diene polymer composition, method for producing same, and tire 中化学科学技术研究有限公司 2024-05-10 CN claimed
EP-1479698-B1 Method for producing modified conjugated diene polymer and rubber composition JSR CORP (JP) 2008-05-14 EP claimed
US-7202306-B2 Method for producing modified conjugated diene polymer and rubber composition JSR CORPORATION (JP) 2007-04-10 US claimed
US-20060264560-A1 Method for producing modified conjugated diene polymer and rubber composition JSR CORPORATION (JP) 2006-11-23 US claimed
US-20050009979-A1 Method for producing modified conjugated diene polymer and rubber composition JSR CORPORATION (JP) 2005-01-13 US claimed
EP-1479698-A1 Method for producing modified conjugated diene polymer and rubber composition JSR Corporation (JP) 2004-11-24 EP claimed
EP-3733756-B1 TREAD RUBBER COMPOSITION FOR STUDLESS WINTER TIRES SUMITOMO RUBBER IND (JP) 2026-01-28 EP disclosed
EP-4055098-B1 TIRE HAVING TREAD OF SPECIFIED RUBBER COMPOSITION AND RELATED METHODS BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2025-12-24 EP disclosed
EP-4662253-A2 METHOD FOR PREPARING MONOMODAL POLYISOPRENE WITH DILITHIUM INITIATORS BRIDGESTONE CORPORATION (JP) 2025-12-17 EP disclosed
EP-4646450-A1 LINEAR TELECHELIC DIENE COPOLYMERS AND THEIR USE IN TIRE COMPONENTS BRIDGESTONE CORPORATION (JP) 2025-11-12 EP disclosed
US-12466214-B2 Tire tread rubber composition BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-11-11 US disclosed
US-20250333585-A1 Tire Tread Rubber Composition BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-10-30 US disclosed
US-12415907-B2 Rubber composition and run-flat tire BRIDGESTONE CORPORATION (JP) 2025-09-16 US disclosed
US-20050020757-A1 Process for producing modified polymer modified polymer obtained by the process and rubber composition BRIDGESTONE CORPORATION (JP) 2005-01-27 US disclosed
US-20050009979-A1 Method for producing modified conjugated diene polymer and rubber composition JSR CORPORATION (JP) 2005-01-13 US disclosed
EP-1479698-A1 Method for producing modified conjugated diene polymer and rubber composition JSR Corporation (JP) 2004-11-24 EP disclosed
EP-1462459-A1 PROCESS FOR PRODUCING MODIFIED POLYMER, MODIFIED POLYMER OBTAINED BY THE PROCESS, AND RUBBER COMPOSITION Bridgestone Corporation (JP) 2004-09-29 EP disclosed
EP-1449857-A1 CONJUGATED DIENE POLYMER, PROCESS FOR ITS PRODUCTION AND RUBBER COMPOSITIONS CONTAINING THE SAME Bridgestone Corporation (JP) 2004-08-25 EP disclosed
EP-1297974-A1 PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2003-04-02 EP disclosed
US-20030015272-A1 Pneumatic tire BRIDGESTONE CORPORATION (JP) 2003-01-23 US disclosed