Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.55 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 2/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13487155 | 0.94 | CYP1A2 (0.57) | CYP1A2CYP2A6TERTAPPALDH1A1 | |
| SCHEMBL29475635 | 0.82 | CYP2A6 (0.76) | CYP1A2CYP2A6ALDH1A1MAPK1SIGMAR1 | |
| SCHEMBL1878783 | 0.82 | CYP2A6 (0.76) | CYP1A2CYP2A6ALDH1A1MAPK1SIGMAR1 | |
| SCHEMBL12363750 | 0.82 | CYP1A2 (0.53) | CYP1A2CYP2A6TERTSIGMAR1AKR1C3 | |
| SCHEMBL15131776 | 0.78 | SIGMAR1 (0.47) | CYP1A2CYP2A6TERTAPPALDH1A1 | |
| SCHEMBL9066719 | 0.78 | TERT (0.57) | CYP1A2TERTAPPALDH1A1TSHR | |
| SCHEMBL13432618 | 0.77 | CYP1A2 (0.74) | CYP1A2CYP2A6SIGMAR1AKR1C3AKR1C2 | |
| SCHEMBL14311184 | 0.76 | APP (0.45) | CYP2A6TERTAPPALDH1A1TSHR | |
| SCHEMBL6044185 | 0.76 | APP (0.49) | CYP1A2CYP2A6TERTAPPALDH1A1 | |
| SCHEMBL12292317 | 0.75 | CYP1A2 (0.50) | CYP1A2CYP2A6APPALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230062022-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | NUVATION BIO INC (US) | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230062022-A1 | HETEROCYCLIC COMPOUNDS AS KINASE INHIBITORS | CDK4, CDK6, CDK8 | CYP1A2 3068/4885CYP2A6 1221/4885TERT 548/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.