Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | TERT | O14746 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CALM1 | P0DP23 | 2/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA3 | P07451 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13487155 | 0.82 | CYP1A2 (0.57) | APPTERTALDH1A1TSHRCYP3A4 | |
| SCHEMBL14311184 | 0.80 | APP (0.45) | APPTERTALDH1A1TSHRCYP3A4 | |
| SCHEMBL29749150 | 0.80 | CA2 (0.54) | TSHRCA12CA2CA3CA4 | |
| SCHEMBL12566471 | 0.80 | TERT (0.64) | APPTERTALDH1A1TSHRCYP3A4 | |
| SCHEMBL1206769 | 0.80 | CA2 (0.54) | TSHRCA12CA2CA3CA4 | |
| SCHEMBL15131776 | 0.78 | SIGMAR1 (0.47) | APPTERTALDH1A1TSHRCYP3A4 | |
| SCHEMBL165131 | 0.78 | ALDH1A1 (0.64) | APPALDH1A1TSHRCYP3A4MAPK1 | |
| SCHEMBL14311185 | 0.77 | SIGMAR1 (0.46) | APPTERTALDH1A1TSHRCYP3A4 | |
| SCHEMBL25085593 | 0.76 | CYP1A2 (0.55) | APPTERTALDH1A1TSHRCYP3A4 | |
| SCHEMBL5593599 | 0.75 | CYP1A2 (0.51) | ALDH1A1CYP3A4ALOX15CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048604-A1 | Ligands for Aldoketoreductases | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2010-02-25 | — | — | US | disclosed |
| US-20100048604-A1 | Ligands for Aldoketoreductases | TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2010-02-25 | — | — | US | disclosed |
| US-20060142311-A1 | Prodan-containing nucleotide and use thereof | KYOTO UNIVERSITY | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048604-A1 | Ligands for Aldoketoreductases | AKR1C2, AKR1C1, AKR1B1 | APP 3894/4885TERT 3087/4885ALDH1A1 18/4885 |
| US-20060142311-A1 | Prodan-containing nucleotide and use thereof | PNP, NUDT1, NT5C2 | APP 1109/4885TERT 499/4885ALDH1A1 1902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.