Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 7/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 9/20 | 0.34 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618199 | 0.87 | SSTR4 (0.40) | MAPK1SSTR4SSTR1P2RX7 | |
| SCHEMBL2511940 | 0.82 | SSTR4 (0.41) | SSTR4SSTR1 | |
| SCHEMBL2512535 | 0.82 | TAS1R3 (0.42) | SSTR4 | |
| SCHEMBL2515168 | 0.82 | SSTR4 (0.40) | SSTR4SSTR1 | |
| SCHEMBL2514146 | 0.82 | SSTR4 (0.40) | SSTR4SSTR1 | |
| SCHEMBL2513236 | 0.82 | SSTR4 (0.40) | SSTR4SSTR1 | |
| SCHEMBL621967 | 0.81 | SSTR4 (0.38) | MAPK1SSTR4SSTR1P2RX7NTRK1 | |
| SCHEMBL17057377 | 0.79 | SSTR4 (0.37) | SSTR4SSTR1P2RX7 | |
| SCHEMBL2508423 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL627058 | 0.76 | SSTR4 (0.41) | SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592592-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | MAPK1 4532/4885SSTR4 156/4885SSTR1 192/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.