Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 12/20 | 0.37 |
| ▸ | SSTR1 | P30872 | 4/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL618199 | 0.90 | SSTR4 (0.40) | SSTR4SSTR1P2RX7 | |
| SCHEMBL621576 | 0.86 | TAS1R3 (0.46) | SSTR4ACHE | |
| SCHEMBL622154 | 0.82 | SSTR4 (0.50) | SSTR4SSTR1 | |
| SCHEMBL621967 | 0.82 | SSTR4 (0.38) | SSTR4SSTR1P2RX7 | |
| SCHEMBL21281237 | 0.81 | TAS1R3 (0.41) | SSTR4SSTR1 | |
| SCHEMBL626629 | 0.81 | SSTR4 (0.48) | SSTR4SSTR1 | |
| SCHEMBL619016 | 0.81 | SSTR4 (0.48) | SSTR4SSTR1 | |
| SCHEMBL627248 | 0.80 | SSTR4 (0.48) | SSTR4SSTR1 | |
| SCHEMBL626291 | 0.80 | SSTR4 (0.48) | SSTR4SSTR1 | |
| SCHEMBL619254 | 0.80 | SSTR4 (0.48) | SSTR4SSTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | SENOMYX, INC. (US) | 2019-04-02 | — | — | US | disclosed |
| US-9902737-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2018-02-27 | — | — | US | disclosed |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | FIRMENICH INCORPORATED | 2016-09-01 | — | — | US | disclosed |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | FIRMENICH INCORPORATED | 2015-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10244779-B2 | Method of improving stability of sweet enhancer and composition containing stabilized sweet enhancer | TFEB, TREH, SLC2A8 | SSTR4 2147/4885SSTR1 2142/4885HTR1A 4395/4885 |
| US-20150245642-A1 | METHOD OF IMPROVING STABILITY OF SWEET ENHANCER AND COMPOSITION CONTAINING STABILIZED SWEET ENHANCER | TFEB, TREH, SLC2A8 | SSTR4 2147/4885SSTR1 2142/4885HTR1A 4395/4885 |
| US-20160251372-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | SSTR4 156/4885SSTR1 192/4885HTR1A 2609/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.