Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 1/20 | 0.39 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.39 |
| ▸ | PTK6 | Q13882 | 3/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.34 |
| ▸ | LATS1 | O95835 | 1/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.32 |
| ▸ | CSF1R | P07333 | 2/20 | 0.31 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.31 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.31 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.31 |
| ▸ | AURKA | O14965 | 3/20 | 0.31 |
| ▸ | FLT3 | P36888 | 3/20 | 0.31 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30312602 | 0.99 | CTNNB1 (0.39) | CTNNB1TCF7L2PTK6IRAK4LATS1 | |
| SCHEMBL25097176 | 0.92 | PTK6 (0.34) | CTNNB1TCF7L2PTK6IRAK4AURKB | |
| Hydrochloric Acid SCHEMBL30312636 | 0.92 | LCK (0.34) | CTNNB1TCF7L2PTK6IRAK4AURKB | |
| SCHEMBL25097181 | 0.91 | HTR1A (0.31) | CTNNB1TCF7L2IRAK4 | |
| SCHEMBL25096256 | 0.89 | PTK6 (0.36) | CTNNB1TCF7L2PTK6AURKB | |
| SCHEMBL30217847 | 0.88 | FGFR3 (0.40) | CTNNB1TCF7L2PTK6IRAK4LATS1 | |
| SCHEMBL25097072 | 0.88 | FGFR3 (0.40) | CTNNB1TCF7L2PTK6IRAK4LATS1 | |
| SCHEMBL25095792 | 0.87 | KIF18A (0.33) | — | |
| SCHEMBL26769278 | 0.87 | IRAK4 (0.41) | CTNNB1TCF7L2PTK6IRAK4LATS1 | |
| SCHEMBL30312601 | 0.87 | MAPK1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |