Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTK6 | Q13882 | 2/20 | 0.34 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.34 |
| ▸ | LCK | P06239 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 4/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.32 |
| ▸ | PLK1 | P53350 | 1/20 | 0.32 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KIF18A | Q8NI77 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30312636 | 0.99 | LCK (0.34) | PTK6AURKBLCKROCK2ABL1 | |
| SCHEMBL25096247 | 0.92 | CTNNB1 (0.39) | PTK6AURKBLCKIRAK4CTNNB1 | |
| Hydrochloric Acid SCHEMBL30312602 | 0.92 | CTNNB1 (0.39) | PTK6AURKBLCKIRAK4CTNNB1 | |
| SCHEMBL25095792 | 0.92 | KIF18A (0.33) | KIF18A | |
| SCHEMBL25096536 | 0.89 | KDM4E (0.36) | PTK6AURKBLCKROCK2ABL1 | |
| SCHEMBL25096256 | 0.89 | PTK6 (0.36) | PTK6AURKBCTNNB1TCF7L2 | |
| SCHEMBL30217685 | 0.88 | ROCK2 (0.36) | PTK6AURKBLCKROCK2ABL1 | |
| SCHEMBL25096360 | 0.88 | ROCK2 (0.36) | PTK6AURKBLCKROCK2ABL1 | |
| SCHEMBL25096817 | 0.88 | ROCK2 (0.35) | PTK6AURKBLCKROCK2ABL1 | |
| SCHEMBL25096988 | 0.88 | ABL1 (0.39) | PTK6AURKBLCKROCK2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |