Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.31 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30312601 | 0.91 | MAPK1 (0.30) | — | |
| SCHEMBL25096247 | 0.91 | CTNNB1 (0.39) | IRAK4CTNNB1TCF7L2 | |
| Hydrochloric Acid SCHEMBL30312602 | 0.90 | CTNNB1 (0.39) | IRAK4CTNNB1TCF7L2 | |
| SCHEMBL30312593 | 0.89 | LRRK2 (0.35) | HTR1AHTR1DHTR1B | |
| SCHEMBL25095934 | 0.88 | IRAK4 (0.34) | IRAK4 | |
| SCHEMBL25096916 | 0.88 | PRNP (0.39) | — | |
| SCHEMBL25096256 | 0.87 | PTK6 (0.36) | CTNNB1TCF7L2 | |
| SCHEMBL25105002 | 0.86 | HTR1A (0.34) | HTR1AHTR1DHTR1BIRAK4 | |
| SCHEMBL25097176 | 0.86 | PTK6 (0.34) | IRAK4CTNNB1TCF7L2 | |
| SCHEMBL25096252 | 0.86 | WDR5 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023034811-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-03-09 | — | — | WO | disclosed |
| EP-4110464-A1 | COMPOUNDS AND METHODS FOR MODULATING SPLICING | Remix Therapeutics Inc. (US) | 2023-01-04 | — | — | EP | disclosed |