Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21765495 | 0.88 | KDM4E (0.34) | HDAC6LMNABRAFRAB9AKDM4E | |
| SCHEMBL24967875 | 0.80 | NPC1 (0.34) | LMNARAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL13086734 | 0.80 | NPC1 (0.36) | LMNARAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL26859104 | 0.78 | SMN1; SMN2 (0.53) | LMNABRAFRAB9AKDM4ENPC1 | |
| SCHEMBL25680997 | 0.78 | RAB9A (0.41) | HDAC6LMNABRAFRAB9AKDM4E | |
| SCHEMBL24869559 | 0.77 | NPC1 (0.39) | LMNARAB9AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL18555346 | 0.77 | TDP1 (0.48) | LMNARAB9AKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL18819911 | 0.72 | ALDH1A1 (0.33) | RAB9ANPC1ALDH1A1POLBPDE10A | |
| SCHEMBL18611835 | 0.72 | BRAF (0.36) | LMNABRAFRAB9AKDM4ENPC1 | |
| SCHEMBL31048036 | 0.71 | KDM4E (0.38) | HDAC6LMNABRAFRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230071620-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. | 2023-03-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230071620-A1 | PHARMACEUTICAL COMPOUNDS FOR TREATMENT OF MEDICAL DISORDERS | CFD, TFPI, CFH | HDAC6 2861/4885LMNA 1931/4885BRAF 599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.