Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CCR8 | P51685 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30945318 | 1.00 | ALDH1A1 (0.49) | ALDH1A1TDP1CCR1CCR8LMNA | |
| SCHEMBL3294386 | 0.84 | TSHR (0.46) | ALDH1A1TDP1LMNAMAPTKMT2A | |
| Ammonia Solution, Strong SCHEMBL28192999 | 0.81 | ALDH1A1 (0.38) | ALDH1A1LMNAHTTMAPTNPC1 | |
| SCHEMBL3144065 | 0.77 | LMNA (0.41) | ALDH1A1TDP1CCR1CCR8LMNA | |
| Nitric Acid SCHEMBL4305415 | 0.77 | CCR1 (0.48) | ALDH1A1TDP1CCR1CCR8LMNA | |
| SCHEMBL873623 | 0.74 | TSHR (0.43) | ALDH1A1TDP1LMNAMAPTKMT2A | |
| SCHEMBL16289365 | 0.74 | LMNA (0.38) | ALDH1A1TDP1LMNAMAPTNPC1 | |
| SCHEMBL188183 | 0.74 | TSHR (0.38) | ALDH1A1TDP1LMNAMAPTNPC1 | |
| SCHEMBL3865531 | 0.74 | GPR35 (0.45) | ALDH1A1TDP1LMNAHTTMAPT | |
| SCHEMBL4494414 | 0.74 | LMNA (0.38) | ALDH1A1TDP1LMNAMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8481324-B2 | Apparatus and methods for diagnosing renal disorders | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2013-07-09 | — | — | US | claimed |
| US-20110244584-A1 | APPARATUS AND METHODS FOR DIAGNOSING RENAL DISORDERS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2011-10-06 | — | — | US | claimed |
| WO-2010064239-A1 | APPARATUS AND METHODS FOR DIAGNOSING RENAL DISORDERS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2010-06-10 | — | — | WO | claimed |
| EP-4619048-A1 | CYCLEN BASED COMPOUNDS AND THEIR GD(III) COMPLEXES FOR USE AS MULTIMODAL PET/MRI CONTRAST AGENTS | Ustav Organicke Chemie a Biochemie AV CR v.v.i. (CZ) | 2025-09-24 | — | — | EP | disclosed |
| WO-2025126115-A1 | DEGRADATION OF IRAK4 BY CONJUGATION OF IRAK4 INHIBITORS WITH E3 LIGASE LIGANDS AND METHODS OF USE | BEIGENE SWITZERLAND GMBH (CH) | 2025-06-19 | — | — | WO | disclosed |
| WO-2024120557-A1 | CYCLEN BASED COMPOUNDS AND THEIR GD(III) COMPLEXES FOR USE AS MULTIMODAL PET/MRI CONTRAST AGENTS | Ustav Organicke Chemie A Biochemie AV CR v.v.i. (CZ) | 2024-06-13 | — | — | WO | disclosed |
| EP-4382136-A1 | CYCLEN BASED COMPOUNDS AND THEIR GD(III) COMPLEXES FOR USE AS MULTIMODAL PET/MRI CONTRAST AGENTS | Ustav Organicke Chemie A Biochemie Av Cr, V.v.i. (CZ) | 2024-06-12 | — | — | EP | disclosed |
| EP-4337655-A1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS | Bristol-Myers Squibb Company (US) | 2024-03-20 | — | — | EP | disclosed |
| CN-111635288-B | Method for preparing amino compound by catalytic reduction of nitro compound by alkaline earth metal hydride | 新乡市润宇新材料科技有限公司 | 2023-08-11 | — | — | CN | disclosed |
| CN-115073311-B | Efficient preparation of N, N ′ Synthesis method of-di (2-hydroxyethyl) aniline | 河南大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-115073311-A | High-efficiency preparation of N, N ′ Synthesis method of (2-hydroxyethyl) aniline | 河南大学 | 2022-09-20 | — | — | CN | disclosed |
| US-20120264943-A1 | Compounds Suitable As Precursors to Compounds that are Useful for Imaging Amyloid Deposits | ASTRAZENECA AB (SE) | 2012-10-18 | — | — | US | disclosed |
| US-8193363-B2 | Compounds suitable as precursors to compounds that are useful for imaging amyloid deposits | ASTRAZENECA AB (SE) | 2012-06-05 | — | — | US | disclosed |
| US-20110244584-A1 | APPARATUS AND METHODS FOR DIAGNOSING RENAL DISORDERS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2011-10-06 | — | — | US | disclosed |
| WO-2010064239-A1 | APPARATUS AND METHODS FOR DIAGNOSING RENAL DISORDERS | TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD. (IL) | 2010-06-10 | — | — | WO | disclosed |
| US-20100056796-A1 | Compounds Suitable As Precursors to Compounds that are Useful for Imaging Amyloid Deposits | ASTRAZENECA AB (SE) | 2010-03-04 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-7582658-B2 | Bicyclic compound | ASAHI KASEI PHARMA CORPORATION (JP) | 2009-09-01 | — | — | US | disclosed |
| US-20070179295-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
| US-20070179295-A1 | Triazolopyrimidines | BAYER CROPSCIENCE AG (DE) | 2007-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179295-A1 | Triazolopyrimidines | QDPR, DPYD, CYP1B1 | ALDH1A1 431/4885TDP1 131/4885CCR1 3169/4885 |
| US-20100056796-A1 | Compounds Suitable As Precursors to Compounds that are Useful for Imaging Amyloid Deposits | APP, PSEN1, PSEN2 | ALDH1A1 2924/4885TDP1 1248/4885CCR1 3053/4885 |
| US-20120264943-A1 | Compounds Suitable As Precursors to Compounds that are Useful for Imaging Amyloid Deposits | APP, PSEN1, PSEN2 | ALDH1A1 2924/4885TDP1 1248/4885CCR1 3053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.