Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17563594 | 0.78 | CYP11B2 (0.40) | PPARAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL17563595 | 0.78 | CYP11B2 (0.40) | PPARAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL17563596 | 0.78 | CYP11B2 (0.40) | PPARAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL12714261 | 0.77 | KDM1A (0.46) | MAP3K14ESR1ESR2GAAPKM | |
| SCHEMBL1613379 | 0.77 | KDM1A (0.46) | MAP3K14ESR1ESR2GAAPKM | |
| SCHEMBL23376916 | 0.77 | MAP3K14 (0.55) | MAP3K14ESR1ESR2 | |
| SCHEMBL23376859 | 0.77 | MAP3K14 (0.55) | MAP3K14ESR1ESR2 | |
| SCHEMBL15894662 | 0.74 | SIGMAR1 (0.43) | LMNA | |
| SCHEMBL6073558 | 0.74 | RXRA (0.40) | PPARAALDH1A1HPGDALOX15HSD17B10 | |
| SCHEMBL19130238 | 0.74 | SIGMAR1 (0.43) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023030388-A1 | 5-FLUORO-7H-PYRROLO[2,3-D] PYRIMIDINES COMPOUND AS WEE-1 INHIBITOR | 微境生物医药科技(上海)有限公司 | 2023-03-09 | — | — | WO | disclosed |