Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 7/20 | 0.40 |
| ▸ | RXRB | P28702 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 4/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM1A | O60341 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30859520 | 1.00 | RXRA (0.40) | RXRARXRBALDH1A1HPGDALOX15 | |
| SCHEMBL30859519 | 1.00 | RXRA (0.40) | RXRARXRBALDH1A1HPGDALOX15 | |
| SCHEMBL17563594 | 0.81 | CYP11B2 (0.40) | RXRARXRBALDH1A1HPGDALOX15 | |
| SCHEMBL17563596 | 0.81 | CYP11B2 (0.40) | RXRARXRBALDH1A1HPGDALOX15 | |
| SCHEMBL17563595 | 0.81 | CYP11B2 (0.40) | RXRARXRBALDH1A1HPGDALOX15 | |
| SCHEMBL24401065 | 0.79 | KIF11 (0.36) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL24648694 | 0.75 | HSPA9 (0.52) | RXRARXRBALDH1A1HPGDALOX15 | |
| SCHEMBL25100748 | 0.74 | MAP3K14 (0.36) | RXRARXRBALDH1A1HPGDALOX15 | |
| SCHEMBL22589962 | 0.74 | ESR1 (0.35) | RXRARXRBALDH1A1RXRGHTR2A | |
| SCHEMBL9770689 | 0.74 | CYP3A4 (0.41) | RXRARXRBALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486697-A | Synthetic method of salix musk | 安徽金禾化学材料研究所有限公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111285750-B | Device and method for continuous flow synthesis of 1,1-dimethyl-6-tert-butyl indan | 天门市德远化工科技有限公司 | 2022-12-06 | — | — | CN | claimed |
| CN-111285750-A | Device and method for continuous flow synthesis of 1, 1-dimethyl-6-tert-butyl indan | 天门市德远化工科技有限公司 | 2020-06-16 | — | — | CN | claimed |
| US-20030191145-A1 | Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane and their use in human and veterinary medicine and in cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-10-09 | — | — | US | claimed |
| US-6534545-B1 | Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane and their use in human and veterinary medicine and cosmetics | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2003-03-18 | — | — | US | claimed |
| EP-0905118-B1 | Unsaturated 6-tert-butyl-1,1-dimethylindane derivates substituted in the 4-position and their use in human and veterinary medicine as well as in cosmetics | GALDERMA RES & DEV (FR) | 2001-08-16 | — | — | EP | claimed |
| US-6180674-B1 | THERAPY FOR SKIN DISORDERS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2001-01-30 | — | — | US | claimed |
| EP-0905118-A1 | Unsaturated 6-tert-butyl-1,1-dimethylindane derivates substituted in the 4-position and their use in human and veterinary medicine as well as in cosmetics | Galderma Research & Development, S.N.C. (FR) | 1999-03-31 | — | — | EP | claimed |
| CN-117486697-A | Synthetic method of salix musk | 安徽金禾化学材料研究所有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-117486697-A | Synthetic method of salix musk | 安徽金禾化学材料研究所有限公司 | 2024-02-02 | — | — | CN | disclosed |
| CN-111285750-B | Device and method for continuous flow synthesis of 1,1-dimethyl-6-tert-butyl indan | 天门市德远化工科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-111285750-B | Device and method for continuous flow synthesis of 1,1-dimethyl-6-tert-butyl indan | 天门市德远化工科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| CN-111285750-B | Device and method for continuous flow synthesis of 1,1-dimethyl-6-tert-butyl indan | 天门市德远化工科技有限公司 | 2022-12-06 | — | — | CN | disclosed |
| WO-2020150668-A1 | COMPOSITIONS AND METHODS FOR IMMUNE MODULATION AND TREATMENT OF CANCER | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2020-07-23 | — | — | WO | disclosed |
| WO-1998007813-A2 | LAUNDRY DETERGENT COMPOSITIONS COMPRISING β-KETOESTER PRO-FRAGRANCES | THE PROCTER & GAMBLE COMPANY (US) | 1998-02-26 | — | — | WO | disclosed |
| US-4987261-A | Diaminoindane derivatives | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-01-22 | — | — | US | disclosed |
| EP-0040338-A2 | Process for the preparation of acylated indanes and tetrahydronaphthalenes | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1981-11-25 | — | — | EP | disclosed |
| US-4178311-A | Process for the production of compounds useful in perfumery | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-12-11 | — | — | US | disclosed |
| EP-0004914-A1 | Process for the production of compounds useful in perfumery | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-10-31 | — | — | EP | disclosed |
| US-4162256-A | Process for the production of compounds useful in perfumery | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-07-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030191145-A1 | Unsaturated derivatives at the 4-position of 6-tert-butyl-1,1-dimethylindane and their use in human and veterinary medicine and in cosmetics | REL, DERL1, TLR7 | RXRA 30/4885RXRB 44/4885ALDH1A1 491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.