Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | BRS3 | P32247 | 4/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | NMBR | P28336 | 1/20 | 0.43 |
| ▸ | GRPR | P30550 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 2/20 | 0.40 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21290207 | 0.97 | BRS3 (0.44) | FFAR1HCAR2BRS3NR1I2NMBR | |
| SCHEMBL21290196 | 0.94 | BRS3 (0.44) | FFAR1HCAR2BRS3NR1I2NMBR | |
| SCHEMBL21289816 | 0.92 | TGFBR1 (0.44) | FFAR1HCAR2BRS3NR1I2NMBR | |
| SCHEMBL21289802 | 0.92 | FFAR1 (0.41) | FFAR1HCAR2BRS3NR1I2NMBR | |
| SCHEMBL26550027 | 0.91 | FFAR1 (0.44) | FFAR1HCAR2BRS3NR1I2NMBR | |
| SCHEMBL21290226 | 0.90 | TGFBR1 (0.43) | FFAR1HCAR2BRS3NR1I2NMBR | |
| SCHEMBL21290404 | 0.90 | FFAR1 (0.43) | FFAR1HCAR2BRS3NR1I2NMBR | |
| SCHEMBL21290071 | 0.90 | FFAR1 (0.43) | FFAR1HCAR2BRS3NR1I2NMBR | |
| SCHEMBL21290093 | 0.90 | TGFBR1 (0.44) | FFAR1HCAR2BRS3NR1I2NMBR | |
| SCHEMBL21289814 | 0.89 | CYP11B1 (0.46) | FFAR1BRS3NR1I2NMBRGRPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230056324-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2023-02-23 | — | — | US | disclosed |
| WO-2021110720-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2021-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230056324-A1 | METAL COMPLEXES | MCU, IMMT, SOD1 | FFAR1 4874/4885HCAR2 4663/4885BRS3 3897/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.