Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ELANE | P08246 | 3/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | DHFR | P00374 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 2/20 | 0.38 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL621086 | 0.84 | HSD17B10 (0.43) | HSD17B10TP53ELANEPDE10AKMT2A | |
| SCHEMBL618719 | 0.84 | HSD17B10 (0.53) | HSD17B10TP53ELANEPDE10AKMT2A | |
| SCHEMBL17740903 | 0.82 | HSD17B10 (0.51) | HSD17B10TP53PDE10AKMT2AMEN1 | |
| SCHEMBL2513238 | 0.82 | DHODH (0.49) | ELANEPDE10ALMNAALDH1A1HPGD | |
| SCHEMBL2515197 | 0.80 | ALDH1A1 (0.43) | HSD17B10ELANEKMT2AMEN1LMNA | |
| SCHEMBL20015743 | 0.80 | TP53 (0.39) | HSD17B10TP53PDE10AKMT2AMEN1 | |
| SCHEMBL20594059 | 0.80 | ELANE (0.42) | HSD17B10TP53ELANEPDE10AKMT2A | |
| SCHEMBL17740994 | 0.79 | HSD17B10 (0.48) | HSD17B10TP53PDE10AKMT2AMEN1 | |
| SCHEMBL619001 | 0.79 | DCPS (0.52) | HSD17B10TP53ELANEPDE10AKMT2A | |
| SCHEMBL2511075 | 0.79 | MEN1 (0.39) | HSD17B10TP53PDE10AKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8592592-B2 | Sweet flavor modifier | SENOMYX, INC. (US) | 2013-11-26 | — | — | US | disclosed |
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | SENOMYS, INC. (US) | 2011-10-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110245353-A1 | SWEET FLAVOR MODIFIER | TAS2R5, TAS2R10, TAS2R50 | HSD17B10 1094/4885TP53 2533/4885ELANE 1465/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.