SCHEMBL25106987

SCHEMBL25106987

Cc1ccc(Oc2ccc(C(=O)c3ccc(OC4CCC(C)CC4)cc3)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
ALDH1A1 P00352 1/20 0.46
MMP13 P45452 3/20 0.45
PARP10 Q53GL7 1/20 0.44
F2 P00734 2/20 0.43
PLG P00747 2/20 0.43
PRSS1 P07477 2/20 0.43
PRSS2 P07478 2/20 0.43
PRSS3 P35030 2/20 0.43
ST14 Q9Y5Y6 2/20 0.43
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
EPHX2 P34913 6/20 0.42
SRD5A2 P31213 2/20 0.41
FAAH O00519 1/20 0.40
MAP4K4 O95819 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14366712 0.83 TEAD4 (0.44) ALDH1A1MMP13SMN1; SMN2EPHX2MAP4K4
SCHEMBL20196968 0.83 FPR2 (0.40) ALDH1A1PARP10EPHX2
SCHEMBL12807880 0.83 FPR2 (0.40) ALDH1A1PARP10EPHX2
SCHEMBL17049541 0.79 ALDH1A1 (0.73) LMNAALDH1A1MMP13PARP10SMN1; SMN2
SCHEMBL10084164 0.79 ALDH1A1 (0.73) LMNAALDH1A1MMP13PARP10SMN1; SMN2
SCHEMBL822938 0.79 ALDH1A1 (0.73) LMNAALDH1A1MMP13PARP10SMN1; SMN2
SCHEMBL822866 0.79 ALDH1A1 (0.73) LMNAALDH1A1MMP13PARP10SMN1; SMN2
SCHEMBL24087885 0.79 ALDH1A1 (0.73) LMNAALDH1A1MMP13PARP10SMN1; SMN2
SCHEMBL16997316 0.79 ALDH1A1 (0.73) LMNAALDH1A1MMP13PARP10SMN1; SMN2
SCHEMBL10001974 0.79 ALDH1A1 (0.73) LMNAALDH1A1MMP13PARP10SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023029341-A1 COLORLESS TRANSPARENT POLYIMIDE RESIN FILM AND PREPARATION METHOD THEREFOR 山东中柔新材料有限公司 2023-03-09 WO disclosed