SCHEMBL25108317

SCHEMBL25108317

Cn1cc(-c2ccc(F)cc2)c(C(O)C(=O)O)n1

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CSNK1D P48730 18/20 0.47
CSNK1E P49674 18/20 0.47
MAPK13 O15264 1/20 0.47
MAPK12 P53778 1/20 0.47
MAPK11 Q15759 1/20 0.47
MAPK14 Q16539 1/20 0.47
USP9X Q93008 1/20 0.44
MAP4K4 O95819 1/20 0.39
EGFR P00533 1/20 0.39
FRK P42685 1/20 0.39
MAPK9 P45984 1/20 0.39
CSNK1A1 P48729 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1257163 0.76 CSNK1D (0.51) CSNK1DCSNK1EMAPK13MAPK12MAPK11
SCHEMBL4826110 0.73 MAPT (0.48) CSNK1DCSNK1EMAPK13MAPK12MAPK11
SCHEMBL4826105 0.73 MAPT (0.48) CSNK1DCSNK1EMAPK13MAPK12MAPK11
SCHEMBL23160878 0.72 CSNK1D (0.48) CSNK1DCSNK1EMAPK13MAPK12MAPK11
SCHEMBL10432598 0.72 CSNK1D (0.48) CSNK1DCSNK1EMAPK13MAPK12MAPK11
SCHEMBL4286489 0.70 CSNK1D (0.58) CSNK1DCSNK1EMAPK13MAPK12MAPK11
SCHEMBL29902509 0.70 CSNK1D (0.48) CSNK1DCSNK1EMAPK13MAPK12MAPK11
SCHEMBL22309898 0.70 SLC6A4 (0.50) CSNK1DCSNK1EMAPK13MAPK12MAPK11
SCHEMBL4829307 0.69 CSNK1D (0.54) CSNK1DCSNK1EMAPK13MAPK12MAPK11
SCHEMBL25107502 0.69 USP9X (0.45) USP9X

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230065368-A1 INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X FORMA THERAPEUTICS, INC. 2023-03-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230065368-A1 INHIBITING UBIQUITIN SPECIFIC PEPTIDASE 9X USP9X, USP19, USP39 CSNK1D 797/4885CSNK1E 478/4885MAPK13 782/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.