Bromide

Bromide

SCHEMBL2511005

Br.Cc1c(C)n(C(C)C)c(=[Fe])n1C(C)C

nearest known ligand 0.32

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2509356 0.94 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL3678363 0.67 ALDH1A1 (0.33) ALDH1A1SMN1; SMN2
SCHEMBL27003510 0.67 ALDH1A1 (0.37) ALDH1A1SMN1; SMN2
Bromide SCHEMBL2511004 0.65 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL2757599 0.60 ADORA2B (0.38) ALDH1A1SMN1; SMN2
SCHEMBL18407474 0.59 ALDH1A1 (0.32) ALDH1A1SMN1; SMN2
SCHEMBL19657080 0.57 ALDH1A1 (0.56) ALDH1A1SMN1; SMN2
SCHEMBL12368445 0.57 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2
SCHEMBL2757589 0.56 GAA (0.40) ALDH1A1SMN1; SMN2
SCHEMBL14226110 0.56 ALDH1A1 (0.30) ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8034971-B2 Method for producing 1,2-phenylethane compound using atom transfer radical coupling reaction NIPPON SODA CO., LTD. (JP) 2011-10-11 US disclosed
US-20090275772-A1 Metrod for Producing 1,2-Phenylethane Compound Using Atom Transfer Radical Coupling Reaction NIPPON SODA CO., LTD. (JP) 2009-11-05 US disclosed
US-7579401-B2 Block polymer of polymethoxypolyethylene glycol monomethyl methacrylate and polystyrene; LiClO4 a lithium salt as electrolyte; living copolymerization, block polymerization; excellent thermal characteristics, physical characteristics, and ionic conductivity; secondary batteries NIPPON SODA CO., LTD. (JP) 2009-08-25 US disclosed
EP-1997798-A1 METHOD FOR PRODUCING 1,2-PHENYLETHANE COMPOUND USING ATOM TRANSFER RADICAL COUPLING REACTION Nippon Soda Co., Ltd. (JP) 2008-12-03 EP disclosed
EP-1553117-B1 SOLID POLYMER ELECTROLYTE NIPPON SODA CO (JP) 2007-01-17 EP disclosed
US-20050256256-A1 Block polymer of polymethoxypolyethylene glycol monomethyl methacrylate and polystyrene; LiClO4 a lithium salt as electrolyte; living copolymerization, block polymerization; excellent thermal characteristics, physical characteristics, and ionic conductivity; secondary batteries NIPPON SODA CO., LTD (JP) 2005-11-17 US disclosed
EP-1553117-A1 SOLID POLYMER ELECTROLYTE NIPPON SODA CO., LTD. (JP) 2005-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090275772-A1 Metrod for Producing 1,2-Phenylethane Compound Using Atom Transfer Radical Coupling Reaction ROS1, MET, MT-CO1 ALDH1A1 74/4885SMN1; SMN2 3254/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.