Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SYK | P43405 | 6/20 | 0.45 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13232027 | 0.87 | L3MBTL1 (0.56) | L3MBTL1SYKIP6K1KDM4EACVR1 | |
| SCHEMBL7600928 | 0.78 | L3MBTL1 (0.49) | L3MBTL1IP6K1KDM4EACVR1MEN1 | |
| SCHEMBL21025561 | 0.78 | MEN1 (0.47) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL22393621 | 0.77 | MEN1 (0.48) | MEN1KMT2APOLBMAPTSMN1; SMN2 | |
| SCHEMBL5312155 | 0.77 | L3MBTL1 (0.48) | L3MBTL1SYKIP6K1KDM4EACVR1 | |
| SCHEMBL12177224 | 0.77 | L3MBTL1 (0.48) | L3MBTL1SYKIP6K1KDM4EACVR1 | |
| SCHEMBL1500289 | 0.77 | L3MBTL1 (0.48) | L3MBTL1IP6K1KDM4EACVR1MEN1 | |
| SCHEMBL30186355 | 0.77 | ESR1 (0.62) | L3MBTL1SYKIP6K1KDM4EACVR1 | |
| SCHEMBL9919057 | 0.77 | F2RL3 (0.51) | L3MBTL1IP6K1KDM4EACVR1KMT2A | |
| SCHEMBL762008 | 0.76 | GRM5 (0.49) | KDM4EKMT2APOLBMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230065217-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS | ESCIENT PHARMACEUTICALS, INC. | 2023-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230065217-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND METHODS | MRGPRX2, MRGPRX1, MRGPRX4 | L3MBTL1 4099/4885SYK 2351/4885IP6K1 2183/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.