Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | NSD3 | Q9BZ95 | 3/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9919060 | 0.86 | L3MBTL1 (0.59) | L3MBTL1IP6K1KDM4EACVR1ALDH1A1 | |
| SCHEMBL7600928 | 0.81 | L3MBTL1 (0.49) | L3MBTL1IP6K1KDM4EACVR1HDAC3 | |
| SCHEMBL30186355 | 0.79 | ESR1 (0.62) | L3MBTL1IP6K1KDM4EACVR1SYK | |
| SCHEMBL1500289 | 0.79 | L3MBTL1 (0.48) | L3MBTL1IP6K1KDM4EACVR1ALDH1A1 | |
| SCHEMBL9919057 | 0.79 | F2RL3 (0.51) | L3MBTL1IP6K1KDM4EACVR1ALDH1A1 | |
| SCHEMBL12177224 | 0.79 | L3MBTL1 (0.48) | L3MBTL1IP6K1KDM4EACVR1SYK | |
| SCHEMBL25111597 | 0.77 | L3MBTL1 (0.46) | L3MBTL1IP6K1KDM4EACVR1SYK | |
| SCHEMBL9922440 | 0.77 | KDM4E (0.51) | L3MBTL1IP6K1KDM4EACVR1SYK | |
| SCHEMBL9922700 | 0.77 | L3MBTL1 (0.46) | L3MBTL1IP6K1KDM4EACVR1SYK | |
| SCHEMBL9922443 | 0.77 | GABRA1 (0.50) | L3MBTL1IP6K1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007053352-A2 | PYRROLOQUINOLINONE DERIVATIVES AS 5-HYDROXYTRYPTAMINE-6 LIGANDS | WYETH (US) | 2007-05-10 | — | — | WO | disclosed |
| US-20070099911-A1 | Pyrroloquinolinone derivatives as 5-hydroxytryptamine-6 ligands | WYETH (US) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099911-A1 | Pyrroloquinolinone derivatives as 5-hydroxytryptamine-6 ligands | HTR6, HTR5A, HTR2C | L3MBTL1 4551/4885IP6K1 699/4885KDM4E 3529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.