SCHEMBL9919057

SCHEMBL9919057

Cn1cnc2cc(Cl)ccc2c1=O

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 1/20 0.51
L3MBTL1 Q9Y468 1/20 0.48
ALDH1A1 P00352 1/20 0.47
PDE5A O76074 1/20 0.46
IP6K1 Q92551 1/20 0.46
KMT2A Q03164 1/20 0.45
RXFP1 Q9HBX9 1/20 0.44
KDM4E B2RXH2 1/20 0.43
RAB9A P51151 1/20 0.43
ACVR1 Q04771 2/20 0.43
NR4A2 P43354 1/20 0.42
SOS2 Q07890 1/20 0.42
LMNA P02545 1/20 0.41
MAPT P10636 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9919058 0.86 L3MBTL1 (0.59) F2RL3L3MBTL1ALDH1A1IP6K1KMT2A
SCHEMBL7600928 0.81 L3MBTL1 (0.49) F2RL3L3MBTL1ALDH1A1IP6K1KMT2A
SCHEMBL12177224 0.79 L3MBTL1 (0.48) F2RL3L3MBTL1ALDH1A1IP6K1KDM4E
SCHEMBL1500289 0.79 L3MBTL1 (0.48) L3MBTL1ALDH1A1IP6K1KMT2AKDM4E
SCHEMBL5312155 0.79 L3MBTL1 (0.48) L3MBTL1ALDH1A1IP6K1KDM4EACVR1
SCHEMBL30186355 0.79 ESR1 (0.62) L3MBTL1ALDH1A1IP6K1KDM4EACVR1
SCHEMBL12825983 0.79 CYP1A2 (0.47) ALDH1A1PDE5AKMT2ARAB9ANR4A2
SCHEMBL2040470 0.78 KDM4E (0.46) L3MBTL1ALDH1A1IP6K1KMT2AKDM4E
SCHEMBL9217204 0.77 DPP4 (0.44) ALDH1A1NR4A2SOS2CYP1A2
SCHEMBL25111597 0.77 L3MBTL1 (0.46) L3MBTL1ALDH1A1IP6K1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12496297-B1 Compositions of autophagy modulating agents and uses thereof WASHINGTON UNIVERSITY (US) 2025-12-16 US disclosed
EP-4337662-A1 C-LINKED INHIBITORS OF ENL/AF9 YEATS Bridge Medicines (US) 2024-03-20 EP disclosed
WO-2022240830-A1 C-LINKED INHIBITORS OF ENL/AF9 YEATS BRIDGE MEDICINES (US) 2022-11-17 WO disclosed
US-9655363-B2 Microbiocides SYNGENTA PARTICIPATIONS AG (CH) 2017-05-23 US disclosed
US-9655363-B2 Microbiocides SYNGENTA PARTICIPATIONS AG (CH) 2017-05-23 US disclosed
EP-2951167-B1 NOVEL MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2017-01-25 EP disclosed
US-20150351402-A1 NOVEL MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-12-10 US disclosed
US-20150351402-A1 NOVEL MICROBIOCIDES SYNGENTA PARTICIPATIONS AG (CH) 2015-12-10 US disclosed
US-20140221405-A1 PLATELET ADP RECEPTOR INHIBITORS PORTOLA PHARMACEUTICALS, INC. (US) 2014-08-07 US disclosed
US-8524721-B2 Platelet ADP receptor inhibitors PORTOLA PHARMACEUTICALS, INC. (US) 2013-09-03 US disclosed
WO-2011032159-A1 METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT META COMESTICS, LLC (US) 2011-03-17 WO disclosed
US-20110002866-A1 METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT LUBIT BEVERLY W 2011-01-06 US disclosed
US-20100234350-A1 PLATELET ADP RECEPTOR INHIBITORS PORTOLA PHARMACEUTICALS, INC. (US) 2010-09-16 US disclosed
WO-2010039535-A1 COMPOSITIONS AND METHODS TO TREAT EPITHELIAL-RELATED CONDITIONS META COSMETICS, LLC (US) 2010-04-08 WO disclosed
US-7622474-B2 Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis PORTOLA PHARMACEUTICALS, INC. (US) 2009-11-24 US disclosed
US-7622474-B2 Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis PORTOLA PHARMACEUTICALS, INC. (US) 2009-11-24 US disclosed
US-20080194597-A1 Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis PORTOLA PHARMACEUTICALS, INC. (US) 2008-08-14 US disclosed
US-20080194597-A1 Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis PORTOLA PHARMACEUTICALS, INC. (US) 2008-08-14 US disclosed
US-7358257-B2 sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives; effective for prevention and treatment of cardiovascular diseases, antithrombotic agents PORTOLA PHARMACEUTICALS, INC. (US) 2008-04-15 US disclosed
US-7358257-B2 sulfonylurea derivatives, sulfonylthiourea derivatives, sulfonylguanidine derivatives, sulfonylcyanoguanidine derivatives, thioacylsulfonamide derivatives, and acylsulfonamide derivatives; effective for prevention and treatment of cardiovascular diseases, antithrombotic agents PORTOLA PHARMACEUTICALS, INC. (US) 2008-04-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110002866-A1 METHODS TO PREVENT A HAIR-RELATED SIDE EFFECT OF TREATMENT WITH A CHEMOTHERAPEUTIC AGENT PGF, PTGS1, PTGS2 F2RL3 4779/4885L3MBTL1 2318/4885ALDH1A1 498/4885
US-20100234350-A1 PLATELET ADP RECEPTOR INHIBITORS TBXA2R, GP6, P2RY6 F2RL3 118/4885L3MBTL1 4542/4885ALDH1A1 1369/4885
US-20080194597-A1 Asulfonyl(urea, thiourea, guanidine, cyanoguanidine) compounds; cardiovascular disorders; thrombosis PIGS, GP6, ASGR1 F2RL3 1647/4885L3MBTL1 3635/4885ALDH1A1 1520/4885
US-20140221405-A1 PLATELET ADP RECEPTOR INHIBITORS PTAFR, ADGRF1, P2RY6 F2RL3 113/4885L3MBTL1 4704/4885ALDH1A1 760/4885
US-20150351402-A1 NOVEL MICROBIOCIDES MSR1, C1R, CD14 F2RL3 64/4885L3MBTL1 644/4885ALDH1A1 2776/4885
US-12496297-B1 Compositions of autophagy modulating agents and uses thereof BECN1, TFEB, ATG7 F2RL3 4387/4885L3MBTL1 2665/4885ALDH1A1 3863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.