Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 3/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2B | P41595 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | XPO1 | O14980 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25112281 | 0.82 | IDO1 (0.50) | IDO1PPARGTACR1MAPTRAPGEF4 | |
| SCHEMBL998165 | 0.80 | IDO1 (0.46) | IDO1MAPTRAPGEF4LMNAXPO1 | |
| SCHEMBL26074528 | 0.80 | IDO1 (0.46) | IDO1SIGMAR1TACR1MAPTHTR2A | |
| SCHEMBL11582599 | 0.80 | SIGMAR1 (0.39) | IDO1SIGMAR1MAPTRAPGEF4LMNA | |
| SCHEMBL148275 | 0.80 | IDO1 (0.52) | IDO1SIGMAR1TACR1MAPTHTR2A | |
| Hydrochloric Acid SCHEMBL999258 | 0.78 | IDO1 (0.48) | IDO1MAPTRAPGEF4LMNAXPO1 | |
| SCHEMBL17994007 | 0.76 | MAPT (0.50) | MAPTLMNAALDH1A1GPR35 | |
| SCHEMBL16715359 | 0.76 | PPARG (0.50) | PPARGLMNASLC6A4ALDH1A1 | |
| SCHEMBL14117049 | 0.75 | CCR2 (0.39) | TACR1ALDH1A1 | |
| SCHEMBL25112073 | 0.75 | MAPT (0.43) | IDO1TACR1MAPTRAPGEF4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023036217-A1 | ACRYLAMIDE COMPOUND AND USE THEREOF | 南京明德新药研发有限公司 | 2023-03-16 | — | — | WO | disclosed |