SCHEMBL998165

SCHEMBL998165

NNc1cc(C(F)(F)F)cc(C(F)(F)F)c1

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 3/20 0.46
MAPT P10636 1/20 0.45
RAPGEF4 Q8WZA2 1/20 0.45
XPO1 O14980 1/20 0.42
GPR35 Q9HC97 1/20 0.42
P2RX1 P51575 5/20 0.41
LMNA P02545 1/20 0.41
CES2 O00748 1/20 0.41
ALDH1A1 P00352 1/20 0.40
ACP1 P24666 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA9 Q16790 1/20 0.40
IKBKE Q14164 1/20 0.39
P2RX4 Q99571 1/20 0.38
P2RX7 Q99572 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL999258 0.97 IDO1 (0.48) IDO1MAPTRAPGEF4XPO1GPR35
SCHEMBL25112073 0.89 MAPT (0.43) IDO1MAPTRAPGEF4XPO1GPR35
SCHEMBL997922 0.86 HDAC3 (0.42) IDO1MAPTRAPGEF4XPO1GPR35
SCHEMBL11677821 0.84 RAPGEF4 (0.52) IDO1MAPTRAPGEF4XPO1GPR35
SCHEMBL4374429 0.84 RAPGEF4 (0.53) IDO1MAPTRAPGEF4XPO1GPR35
Hydrochloric Acid SCHEMBL28844636 0.83 ACP1 (0.46) IDO1XPO1GPR35ACP1P2RX4
Hydrochloric Acid SCHEMBL4376336 0.83 RAPGEF4 (0.51) IDO1MAPTRAPGEF4XPO1GPR35
SCHEMBL25112072 0.81 TACR1 (0.35) IDO1MAPTRAPGEF4XPO1GPR35
SCHEMBL25112282 0.80 IDO1 (0.44) IDO1MAPTRAPGEF4XPO1GPR35
SCHEMBL11679489 0.80 RAPGEF4 (0.36) IDO1MAPTRAPGEF4XPO1GPR35

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115124441-B Preparation method of No Bo Suan hydrazide compound, product and application thereof 南京林业大学 2024-04-02 CN claimed
CN-115124441-A Preparation method of nopyl acid hydrazide compounds, nopyl acid hydrazide compounds and application of nopyl acid hydrazide compounds 南京林业大学 2022-09-30 CN claimed
CN-101065358-B 3-arylamino pyridine derivatives MERCK SERONO SA 2015-03-11 CN claimed
CN-101065358-A 3-arylamino pyridine derivatives APPLIED RESEARCH SYSTEMS (AN) 2007-10-31 CN claimed
US-20260028360-A1 Metal Complex, Semiconductor Layer Comprising a Metal Complex and Organic Electronic Device NOVALED GMBH (DE) 2026-01-29 US disclosed
US-12454502-B2 Synthesis of deuterated aldehydes ARIZONA BOARD OF REGENTS ON BEHALF OF ATHE UNIVERSITY OF ARIZONA (US) 2025-10-28 US disclosed
EP-4601446-A1 ORGANIC PHOTODETECTOR COMPRISING A METAL COMPLEX OF FORMULA (I), AN ORGANIC ELECTRONIC DEVICE COMPRISING THE ORGANIC PHOTOTECTOR AS WELL AS A DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2025-08-13 EP disclosed
EP-4600240-A1 ORGANIC ELECTRONIC DEVICE COMPRISING A METAL COMPLEX OF FORMULA (I) AS WELL AS A DISPLAY DEVICE COMPRISING THE ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2025-08-13 EP disclosed
EP-4568947-A1 METAL COMPLEX, SEMICONDUCTOR LAYER COMPRISING A METAL COMPLEX AND ORGANIC ELECTRONIC DEVICE Novaled GmbH (DE) 2025-06-18 EP disclosed
CN-119677721-A Metal complex, semiconductor layer containing metal complex, and organic electronic device 诺瓦尔德股份有限公司 2025-03-21 CN disclosed
CN-115124441-B Preparation method of No Bo Suan hydrazide compound, product and application thereof 南京林业大学 2024-04-02 CN disclosed
WO-2024033322-A1 METAL COMPLEX, SEMICONDUCTOR LAYER COMPRISING A METAL COMPLEX AND ORGANIC ELECTRONIC DEVICE NOVALED GMBH (DE) 2024-02-15 WO disclosed
EP-0457182-B1 Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor BOEHRINGER MANNHEIM GMBH (DE) 1997-02-26 EP disclosed
US-5215924-A Water immiscibility; ionophore; pH indicator which undergoes color change; sensitizer/stabilizer BOEHRINGER MANNHEIM GMBH (DE) 1993-06-01 US disclosed
EP-0457182-A2 Method having increased sensitivity, for the determination of an ion, the use of suitable substances and corresponding means therefor Roche Diagnostics GmbH (DE) 1991-11-21 EP disclosed
US-4366155-A 1-Benzoyl-3-(6-oxopyridazinyl)ureas, compositions, and insecticidal method ELI LILLY AND COMPANY (US) 1982-12-28 US disclosed
EP-0063413-A1 1-Benzoyl-3-(heterocyclic)ureas, compositions, and insecticidal method ELI LILLY AND COMPANY (US) 1982-10-27 EP disclosed
US-4045169-A FLUORESCENT DYES HOECHST AKTIENGESELLSCHAFT (DT) 1977-08-30 US disclosed
US-3957815-A 3-[3',4'-Dichloro-6'-alkyl-phenyl]-Δ2 -pyrazoline derivatives and their use as optical brighteners HOECHST AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed
US-3947513-A FUNGICIDES BAYER AKTIENGESELLSCHAFT (DT) 1976-03-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12454502-B2 Synthesis of deuterated aldehydes ADH1C, ADH1A, CBR1 IDO1 345/4885MAPT 4584/4885RAPGEF4 4226/4885
US-20260028360-A1 Metal Complex, Semiconductor Layer Comprising a Metal Complex and Organic Electronic Device AFF4, AFF1, AFF2 IDO1 1555/4885MAPT 4095/4885RAPGEF4 3593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.