Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 4/20 | 0.68 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.54 |
| ▸ | BACE1 | P56817 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127092 | 0.83 | ALDH1A1 (0.61) | KIF11PTPN5BACE1ALDH1A1MAPK1 | |
| SCHEMBL163728 | 0.81 | KIF11 (1.00) | KIF11PTPN5BACE1ALDH1A1TSHR | |
| Biphenyl SCHEMBL27543247 | 0.80 | ALDH1A1 (0.64) | KIF11PTPN5BACE1ALDH1A1MAPK1 | |
| SCHEMBL927399 | 0.80 | ALDH1A1 (0.37) | KIF11ALDH1A1TSHRTAAR1PTPN1 | |
| Water SCHEMBL7382449 | 0.79 | KIF11 (0.95) | KIF11PTPN5BACE1ALDH1A1TSHR | |
| Ammonia Solution, Strong SCHEMBL21809401 | 0.79 | KIF11 (0.95) | KIF11PTPN5BACE1ALDH1A1TSHR | |
| SCHEMBL27887943 | 0.79 | KIF11 (0.95) | KIF11PTPN5BACE1ALDH1A1TSHR | |
| SCHEMBL17035905 | 0.77 | KIF11 (0.65) | KIF11PTPN5BACE1ALDH1A1MAPK1 | |
| SCHEMBL28819791 | 0.77 | KIF11 (0.65) | KIF11PTPN5BACE1ALDH1A1MAPK1 | |
| Nitrogen SCHEMBL261370 | 0.77 | KIF11 (0.90) | KIF11PTPN5BACE1ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230099421-A1 | A NEW METHOD OF 18F LABELLING AND INTERMEDIATE SALTS | NATIONAL UNIVERSITY OF SINGAPORE (SG) | 2023-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230099421-A1 | A NEW METHOD OF 18F LABELLING AND INTERMEDIATE SALTS | NPY1R, TMEM14C, SLCO1B1 | KIF11 1093/4885PTPN5 1790/4885BACE1 1511/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.