Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 7/20 | 0.36 |
| ▸ | PGK1 | P00558 | 1/20 | 0.36 |
| ▸ | PGK2 | P07205 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.35 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.35 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.35 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA5A | P35218 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13205250 | 0.89 | ALDH1A1 (0.53) | ALDH1A1TSHRKIF11CES2CES1 | |
| SCHEMBL1781465 | 0.87 | CA2 (0.50) | ALDH1A1TSHRCES2CES1CA1 | |
| SCHEMBL25119775 | 0.87 | KCNN4 (0.42) | CES2CES1ORAI1ORAI2ORAI3 | |
| SCHEMBL11154793 | 0.84 | TRPV4 (0.37) | — | |
| SCHEMBL25119756 | 0.84 | TSHR (0.52) | ALDH1A1TSHRKIF11CA1CA2 | |
| SCHEMBL12869567 | 0.84 | LMNA (0.47) | TSHR | |
| SCHEMBL127092 | 0.82 | ALDH1A1 (0.61) | ALDH1A1TSHRKIF11PGK1PGK2 | |
| SCHEMBL25119686 | 0.80 | KIF11 (0.68) | ALDH1A1TSHRKIF11CA1CA2 | |
| SCHEMBL1568687 | 0.80 | PDE2A (0.34) | KIF11ESR1ESR2CES2CES1 | |
| SCHEMBL15744389 | 0.78 | PTPN5 (0.48) | ALDH1A1KIF11MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9260364-B2 | Catalytic or photocatalytic preparation method of parylene AF4 | YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) | 2016-02-16 | — | — | US | claimed |
| US-20150218067-A1 | CATALYTIC OR PHOTOCATALYTIC PREPARATION METHOD OF PARYLENE AF4 | YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) | 2015-08-06 | — | — | US | claimed |
| US-9056810-B2 | Photocatalytic preparation method of parylene AF4 | YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) | 2015-06-16 | — | — | US | claimed |
| US-9056809-B2 | Catalytic preparation method of parylene AF4 | YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) | 2015-06-16 | — | — | US | claimed |
| US-20140221632-A1 | PHOTOCATALYTIC PREPARATION METHOD OF PARYLENE AF4 | YUAN-SHIN MATERIALS TECHNOLOGY CORP | 2014-08-07 | — | — | US | claimed |
| US-20140011986-A1 | CATALYTIC OR PHOTOCATALYTIC PREPARATION METHOD OF PARYLENE AF4 | YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) | 2014-01-09 | — | — | US | claimed |
| US-7544765-B2 | Methods for producing thermoplastic fluoropolymers | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-06-09 | — | — | US | claimed |
| US-7465841-B2 | Method and device for purifying 1,4-bis (bromodifluoromethyl) benzene | CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY (TW) | 2008-12-16 | — | — | US | claimed |
| US-20080090992-A1 | Novel methods for producing thermoplastic fluoropolymers | ARKEMA INC. | 2008-04-17 | — | — | US | claimed |
| US-20050256349-A1 | Method and device for purifying 1,4-bis (bromodifluoromethyl) benzene | NATIONAL CHUNG SHAN INSTITUTE OF SCIENCE AND TECHNOLOGY (TW) | 2005-11-17 | — | — | US | claimed |
| EP-1021389-A1 | PROCESSES FOR THE PREPARATION OF OCTAFLUORO- 2,2]PARACYCLOPHANE | SPECIALTY COATING SYSTEMS, INC. (US) | 2000-07-26 | — | — | EP | claimed |
| US-5849962-A | Process for the preparation of octafluoro-(2,2) paracyclophane | SPECIALTY COATING SYSTEMS, INC. (US) | 1998-12-15 | — | — | US | claimed |
| US-5841005-A | REACTING A DIHALO COMPOUND WITH A REDUCING AGENT IN THE PRESENCE OF A TRANSITION METAL CATALYST | SPECIALTY COATING SYSTEMS, INC. | 1998-11-24 | — | — | US | claimed |
| WO-1997014666-A1 | PROCESSES FOR THE PREPARATION OF OCTAFLUORO-[2,2]PARACYCLOPHANE | SPECIALTY COATING SYSTEMS, INC. (US) | 1997-04-24 | — | — | WO | claimed |
| US-5536892-A | Processes for the preparation of octafluoro-[2,2]paracyclophane | SPECIALTY COATING SYSTEMS, INC. (US) | 1996-07-16 | — | — | US | claimed |
| US-20160322638-A1 | HEAT-TREATED POLYMER COATED ELECTRODE ACTIVE MATERIALS | A123 SYSTEMS LLC (US) | 2016-11-03 | — | — | US | disclosed |
| US-9260364-B2 | Catalytic or photocatalytic preparation method of parylene AF4 | YUAN-SHIN MATERIALS TECHNOLOGY CORP. (TW) | 2016-02-16 | — | — | US | disclosed |
| US-5536892-A | Processes for the preparation of octafluoro-[2,2]paracyclophane | SPECIALTY COATING SYSTEMS, INC. (US) | 1996-07-16 | — | — | US | disclosed |
| EP-0549980-A1 | Processes for the preparation of octafluoro-[2,2] paracyclophane | SPECIALTY COATING SYSTEMS, INC. (US) | 1993-07-07 | — | — | EP | disclosed |
| US-5210341-A | Processes for the preparation of octafluoro-[2,2]paracyclophane | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1993-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221632-A1 | PHOTOCATALYTIC PREPARATION METHOD OF PARYLENE AF4 | AFF4, PF4, CYP3A4 | ALDH1A1 876/4885TSHR 3400/4885KIF11 1611/4885 |
| US-20150218067-A1 | CATALYTIC OR PHOTOCATALYTIC PREPARATION METHOD OF PARYLENE AF4 | CYP3A4, AFF4, PF4 | ALDH1A1 699/4885TSHR 2976/4885KIF11 2187/4885 |
| US-20140011986-A1 | CATALYTIC OR PHOTOCATALYTIC PREPARATION METHOD OF PARYLENE AF4 | CYP3A4, AFF4, PF4 | ALDH1A1 699/4885TSHR 2976/4885KIF11 2187/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.