Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27062247 | 0.86 | TDP1 (0.43) | TDP1L3MBTL1CYP2A6HRH3SIGMAR1 | |
| SCHEMBL25751682 | 0.86 | TDP1 (0.43) | TDP1L3MBTL1CYP2A6HRH3HRH1 | |
| SCHEMBL25751679 | 0.82 | TDP1 (0.47) | TDP1L3MBTL1CYP2A6HRH3HRH1 | |
| SCHEMBL25129262 | 0.75 | SIGMAR1 (0.55) | SIGMAR1 | |
| SCHEMBL7452098 | 0.71 | CHRNB2 (0.65) | TDP1L3MBTL1CYP2A6SIGMAR1 | |
| SCHEMBL27345028 | 0.70 | CHRNB2 (0.63) | TDP1L3MBTL1CYP2A6SIGMAR1 | |
| SCHEMBL29485677 | 0.69 | CYP2A6 (0.76) | TDP1L3MBTL1CYP2A6HRH3HRH1 | |
| SCHEMBL29485675 | 0.69 | TDP1 (0.80) | TDP1L3MBTL1CYP2A6HRH3HRH1 | |
| SCHEMBL2843094 | 0.69 | CYP2A6 (0.76) | TDP1L3MBTL1CYP2A6HRH3HRH1 | |
| SCHEMBL724788 | 0.69 | TDP1 (0.80) | TDP1L3MBTL1CYP2A6HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091644-A2 | HSD17B13-RELATED DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023049218-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |