Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 12/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25751677 | 0.82 | SIGMAR1 (0.50) | SIGMAR1POLBLTA4HMAOA | |
| SCHEMBL25129261 | 0.75 | TDP1 (0.47) | SIGMAR1 | |
| SCHEMBL6550825 | 0.71 | SIGMAR1 (1.00) | SIGMAR1POLBLTA4H | |
| SCHEMBL2962629 | 0.71 | SIGMAR1 (1.00) | SIGMAR1POLBLTA4H | |
| SCHEMBL24051990 | 0.71 | MEN1 (0.42) | — | |
| SCHEMBL17117358 | 0.70 | SIGMAR1 (0.56) | SIGMAR1POLBLTA4HMAOA | |
| SCHEMBL3593088 | 0.69 | SIGMAR1 (0.89) | SIGMAR1POLBLTA4H | |
| SCHEMBL13504060 | 0.69 | SIGMAR1 (0.50) | SIGMAR1POLBLTA4H | |
| SCHEMBL919176 | 0.69 | HTR3A (0.57) | SIGMAR1MAOA | |
| SCHEMBL24052066 | 0.68 | GNAI3 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023049218-A1 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2023-03-30 | — | — | WO | disclosed |